Evidence map›Paper›PMID 41876516›Full record

ArticleNature communications2026

Ancient DNA reveals 4000 years of grapevine diversity, viticulture and clonal propagation in France.

Rémi Noraz, Lorelei Chauvey, Stefanie Wagner, Oscar Estrada, Nathan Wales, Emmanuelle Bonnaire, Manon Cabanis, Marie Derreumaux, Isabel Figueiral, Charlotte Hallavant and 32 more

Abstract readHistorical Article
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors.

Rémi NorazCentre d'Anthropobiologie et de Génomique de Toulouse, Université de Toulouse, CNRS UMR 5288, 37 Allées Jules Guesde, Toulouse, France.
Lorelei ChauveyCentre d'Anthropobiologie et de Génomique de Toulouse, Université de Toulouse, CNRS UMR 5288, 37 Allées Jules Guesde, Toulouse, France.ORCID http://orcid.org/0000-0002-5015-3924
Stefanie WagnerCentre d'Anthropobiologie et de Génomique de Toulouse, Université de Toulouse, CNRS UMR 5288, 37 Allées Jules Guesde, Toulouse, France.
Oscar EstradaCentre d'Anthropobiologie et de Génomique de Toulouse, Université de Toulouse, CNRS UMR 5288, 37 Allées Jules Guesde, Toulouse, France.ORCID http://orcid.org/0000-0001-5803-7007
Nathan WalesCentre d'Anthropobiologie et de Génomique de Toulouse, Université de Toulouse, CNRS UMR 5288, 37 Allées Jules Guesde, Toulouse, France.ORCID http://orcid.org/0000-0003-0359-8450
Emmanuelle BonnaireArchéozoloogie, Archéobotanique - Sociétés, Pratiques et Environnement, CNRS-MNHN UMR 7209, 55 rue Buffon, Paris, France.
Manon CabanisInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Marie DerreumauxArchéozoloogie, Archéobotanique - Sociétés, Pratiques et Environnement, CNRS-MNHN UMR 7209, 55 rue Buffon, Paris, France.
Isabel FigueiralISEM, Univ Montpellier, CNRS, IRD, EPHE, Inrap, Montpellier, France.
Charlotte HallavantHadès bureau d'investigation archéologiques, 9 rue d'Ariane, L'Union, France.
Philippe MarinvalASM, Université Paul-Valéry Montpellier, INRAP, Ministère de la culture, Montpellier, France.
Véronique MatterneArchéozoloogie, Archéobotanique - Sociétés, Pratiques et Environnement, CNRS-MNHN UMR 7209, 55 rue Buffon, Paris, France.
Jérôme RosISEM, Univ Montpellier, CNRS, IRD, EPHE, Inrap, Montpellier, France.
Nuria RoviraASM, Université Paul-Valéry Montpellier, INRAP, Ministère de la culture, Montpellier, France.
Margaux TillierASM, Université Paul-Valéry Montpellier, INRAP, Ministère de la culture, Montpellier, France.
Marilyne BovagneInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Jean Chausserie-LapréeService Art, Histoire et Archéologie, 14 cours Aristide Briand, Martigues, France.
Clément NicolasMosaïques Archéologie, Domaine La Barthe, domaine Barthe, Cournonterral, France.
Isabelle DaveauInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
David DelassusService archéologique municipal de Valenciennes, Rue des Archers, Valenciennes, France.
Eric GailledratInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Olivier GinouvezInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Bertrand HouixInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Cécile JungInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Philippe KuchlerMinistère de la Culture, DRAC Grand-Est, Metz, France.
Laure LerouxHadès bureau d'investigation archéologiques, 9 rue d'Ariane, L'Union, France.
Raphaël MacarioHadès bureau d'investigation archéologiques, 9 rue d'Ariane, L'Union, France.
Elise MarlièreAntiquarium-Arqueológia y patrimonio, Avda Isidoro Macabich 19, 07820 Sant Antoni de Portmany, Eivissa- Illes Balears, Spain.
Michel PasqualiniCulture et Environnement, Préhistoire, Antiquité, Moyen-âge, Université Nice Côte d'Azur, CNRS UMR 7264, 24 avenue des Diables Bleus, Nice, France.
Gaël PiquesInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Hervé PomaredesInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Justine RobertHadès bureau d'investigation archéologiques, 9 rue d'Ariane, L'Union, France.
Cédric RomsInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Muriel Roth-ZehnerArchéologie Alsace, 11 rue champollion, Sélestat, France.
Maxime ScrinziMosaïques Archéologie, Domaine La Barthe, domaine Barthe, Cournonterral, France.
Maryanick Taras-ThomasInstitut National de Recherches Archéologiques Préventives, rue d'Alésia, Paris, France.
Josep Torres CostaAntiquarium-Arqueológia y patrimonio, Avda Isidoro Macabich 19, 07820 Sant Antoni de Portmany, Eivissa- Illes Balears, Spain.
Guillaume BesnardCentre de Recherche sur la Biodiversité et l'Environnement, Université de Toulouse, CNRS, IRD, UMR 5300, 118 route de Narbonne, Toulouse, France.ORCID http://orcid.org/0000-0003-2275-6012
Jean-Frédéric TerralISEM, Univ Montpellier, CNRS, IRD, EPHE, Inrap, Montpellier, France.
Roberto BacilieriUMR AGAP Institut, Univ Montpellier, CIRAD, INRAE, Institut Agro, Montpellier, France.ORCID http://orcid.org/0000-0002-3342-362X
Laurent BoubyISEM, Univ Montpellier, CNRS, IRD, EPHE, Inrap, Montpellier, France. laurent.bouby@umontpellier.fr.ORCID http://orcid.org/0000-0002-3633-9829
Ludovic OrlandoCentre d'Anthropobiologie et de Génomique de Toulouse, Université de Toulouse, CNRS UMR 5288, 37 Allées Jules Guesde, Toulouse, France. ludovic.orlando@utoulouse.fr.ORCID http://orcid.org/0000-0003-3936-1850

Funding

Agence Nationale de la Recherche (French National Research Agency) ANR-16-CE27- 0013Agence Nationale de la Recherche (French National Research Agency) ANR-20-CE27-0013Agence Nationale de la Recherche (French National Research Agency) ANR-22-CE27-0026Agence Nationale de la Recherche (French National Research Agency) ANR-23-0003EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) HorsePower-101071707EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) PEGASUS-681605
6 · The paper itself

Abstract

Wine production has deep historical roots in France, yet the biological foundations of early viticulture remain elusive. We report genome-wide ancient DNA data from 49 archaeological grape pips spanning ~4000 years, from the Bronze Age to the Medieval period, primarily focusing on France. Population genetic analyses reveal the genetic makeup of wild local grapevines in the Bronze Age and the early use of domesticated grapevines by ~625-500 BCE. Roman-era genomes reflect long-distance exchange from Iberian, Balkan, Levantine, and Caucasian domesticated varieties. Vegetative propagation, evidenced by genetically identical clones across sites and centuries, emerged by the mid-Iron Age and became a pillar of viticultural practice. Remarkably, one Medieval sample from Valenciennes is genetically identical to modern 'Pinot Noir', demonstrating clonal continuity over nearly 600 years. This study traces the introduction, integration and spread of diverse grapevine ancestries that have contributed to shape the varietal landscape of French viticulture.

Indexed as

DNA, AncientDNA, PlantVitisAgricultureFranceGenetic VariationGenome, PlantHistory, AncientWineDNA, AncientDNA, Plant

Identifiers

PMID41876516
PMCPMC13013926

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.