Evidence map›Paper›PMID 41876410›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

Associations of war-related exposures and early life adversity with late-life cognition.

Oanh L Meyer, Sarah Tomaszewski Farias, Brandon E Gavett, Van T Park, Ladson Hinton, Alka M Kanaya, Rachel A Whitmer, Quyen Q Tiet, Quyen Vuong, Lauren G Mai and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Oanh L MeyerUniversity of California Davis School of Medicine, Sacramento, California, USA.ORCID 0000-0002-1093-0477
Sarah Tomaszewski FariasUniversity of California Davis School of Medicine, Sacramento, California, USA.
Brandon E GavettUniversity of California Davis School of Medicine, Sacramento, California, USA.
Van T ParkUniversity of California San Francisco, San Francisco, California, USA.
Ladson HintonUniversity of California Davis School of Medicine, Sacramento, California, USA.
Alka M KanayaUniversity of California San Francisco, San Francisco, California, USA.
Rachel A WhitmerUniversity of California Davis School of Medicine, Sacramento, California, USA.
Quyen Q TietCalifornia School of Professional Psychology at Alliant University, Emeryville, California, USA.
Quyen VuongInternational Children Assistance Network (ICAN), Milpitas, California, USA.
Lauren G MaiZuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California, USA.
Andrew WeakleyUniversity of California Davis School of Medicine, Sacramento, California, USA.
Uyen M T VuUniversity of California Davis School of Medicine, Sacramento, California, USA.
Briana Alejandra DominguezUniversity of California Davis School of Medicine, Sacramento, California, USA.
Danielle HarveyUniversity of California Davis School of Medicine, Sacramento, California, USA.

Funding

UC Davis Alzheimer's Disease Research CenterP30AG072972 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Charles DeCarli, Rachel A Whitmer · 2021 to 2026
$25.2M
Vietnamese Insights into Cognitive Aging Program (VIP)R01AG067541 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI OANH L MEYER · 2021 to 2026
$10.2M
COVID-19 Effects on the Mental and Physical Health of AAPI Survey Study (COMPASS) IIR24AG063718 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PARK, VAN MY TA · 2019 to 2021
$4.4M
NIA NIH HHS P30 AG072972NIA NIH HHS P30AG072972NIA NIH HHS R01 AG067541NIA NIH HHS R01AG067541NIA NIH HHS R24 AG063718NIA NIH HHS R24AG063718
6 · The paper itself

Abstract

introductionWe examined associations of early life adversity (ELA) and war exposures with late-life cognition of participants in the Vietnamese Insights into Cognitive Aging Program (VIP).

methodsParticipants completed psychosocial and neuropsychological assessments, the latter including measures of global cognition, executive function, semantic memory, episodic memory, and visuospatial skills. Principal component analysis identified four war exposure components (harsh conditions and witnessing death, personal life threat/endangerment, family endangerment, and displacement) that were included in multivariable Bayesian regression models and an ELA composite.

resultsVIP participants' (N = 548) mean age was 73 years, and 55% were women. Having been displaced was associated with lower executive function, but greater ELA was associated with better executive function and language scores. Family endangerment was associated with poorer visuospatial skills. Depression and gender moderated associations between the exposures and cognition. DISCUSSION: Both war exposures and ELA likely impact cognitive aging in nuanced ways.

Indexed as

Adverse Childhood ExperiencesCognitionCognitive AgingWar ExposureAgedAged, 80 and overAgingExecutive FunctionFemaleHumansMaleNeuropsychological TestsVietnam ConflictagingAsian Americanscultural diversitytraumaVietnameseVietnam War

Identifiers

PMID41876410
PMCPMC13093312

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.