Evidence map›Paper›PMID 41876144›Full record

ArticleRMD open2026

Severe impairments in work ability among patients with axSpA and PsA: results from the RABBIT-SpA Register.

Stephanie Lembke, Uta Kiltz, Anja Weiß, Kirsten Karberg, Daniel Bestler, Xenofon Baraliakos, Anne C Regierer

Abstract read
In one paragraph

Article in RMD open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephanie Lembke *German Rheumatology Research Center, Programme Area Epidemiology and Health Services Research, Register Research in Rheumatology, Berlin, Germany.ORCID 0000-0003-0426-0312
Uta Kiltz *Ruhr University Bochum, Bochum, Germany.ORCID 0000-0001-5668-4497
Anja WeißGerman Rheumatology Research Center, Programme Area Epidemiology and Health Services Research, Register Research in Rheumatology, Berlin, Germany.ORCID 0000-0003-2069-2190
Kirsten KarbergPrivate Rheumatology Practice, Berlin, Germany.
Daniel BestlerPrivate Rheumatology Practice, Erfurt, Germany.
Xenofon BaraliakosRuhr University Bochum, Bochum, Germany.ORCID 0000-0002-9475-9362
Anne C RegiererGerman Rheumatology Research Center, Programme Area Epidemiology and Health Services Research, Register Research in Rheumatology, Berlin, Germany Anne.Regierer@drfz.de.ORCID 0000-0003-2456-4049

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the frequency and extent of work ability impairment and explore differences in its degree in relation to sociodemographic, clinical and patient-reported factors in patients with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA).

methodsThis cross-sectional analysis used data from the prospective RABBIT-SpA cohort, including patients aged 18-65 years with physician-confirmed axSpA or PsA. Work ability was assessed in both the axSpA and PsA cohorts using the Work Ability Index (WAI; 7-49 points, higher scores=better work ability), categorised as good/excellent (≥37) or moderate/poor (≤36) according to validated cut-offs. Patients were grouped as employed with good/excellent WAI, employed with moderate/poor WAI or non-employed. Descriptive analyses were conducted.

results2655 patients were analysed (axSpA: 1366; PsA: 1276). In the axSpA cohort, 80% were employed, with 70% reporting moderate/poor WAI (mean 31.6, SD: 7.6). Among patients with PsA, 69% were employed, of whom 71% reported moderate/poor WAI (mean 31.4, SD: 8.1).For both the axSpA and PsA cohorts, compared with individuals with good/excellent WAI, those who were non-employed or had moderate/poor WAI were more often female, older, obese, smokers and had fewer years of education.Individuals with lower inflammatory markers, fewer comorbidities and lower disease activity were mainly in the good/excellent WAI group, while non-employed individuals showed the poorest clinical and patient-reported factors, followed by those with moderate/poor WAI.

conclusionAround 25% of patients of working age with axSpA and PsA were non-employed and two-thirds of employed patients reported moderate/poor work ability. The results underline the importance of enhanced focus on occupational health in rheumatology to identify at-risk patients early.

Indexed as

Arthritis, PsoriaticAxial SpondyloarthritisWork Capacity EvaluationAdolescentAdultAgedCross-Sectional StudiesEmploymentFemaleHumansMaleMiddle AgedProspective StudiesRegistriesSeverity of Illness IndexYoung AdultAxial SpondyloarthritisEpidemiologyPatient Reported Outcome MeasuresPsoriatic ArthritisSpondyloarthritis

Identifiers

PMID41876144
PMCPMC13034314

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.