ReviewInternational dental journal2026
A Decade of cGAS Discovery: Point of Convergence in Oral Diseases.
Review in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
INTRODUCTION AND
aimsTo provide the research progress on the cGAS-STING signalling pathway and its related roles in various oral diseases.
methodsWe reviewed the recent research on cGAS-STING in PubMed. This article summarises recent research achievements in the discovery and confirmation of the cGAS-STING signalling pathway, as well as its biological and immunological roles in various diseases.
resultsThe cGAS-STING pathway and its associated cytokines play a crucial role in host immunity. It plays various roles in antiviral infections and autoimmune diseases, while also playing an important role in tumour surveillance and cellular aging processes. Research has shown that the cGAS-STING pathway affects various oral diseases such as periodontitis, pulp infections, oral mucosal diseases, maxillofacial tumours and many others.
conclusionThe cGAS-STING pathway plays a crucial role in various diseases, and its excessive activation often leads to immune dysregualtion. The role of cGAS-STING in oral diseases needs to be further elucidated CLINICAL RELEVANCE: The cGAS-STING pathway represents a promising target for the development of new therapeutic strategies for a range of oral diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.