Evidence map›Paper›PMID 41875428›Full record

ArticleJMIR formative research2026

Development of a Culturally Adapted Smartphone App (IndigeQuit) Designed to Help American Indian and Alaska Native People Quit Commercial Cigarettes: User-Centered Mixed Methods Study.

Jonathan B Bricker, Margarita Santiago-Torres, Brianna M Sullivan, Kristin E Mull, Hershel W Clark, Camille A Fogel, Soo Bin Hwang, Alison R Keith, Chase Kornacki, Trivia Afraid Of Lightning-Craddock and 7 more

Registry-linked trialAbstract read
In one paragraph

Article in JMIR formative research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06145763 (Digital Smoking Cessation Intervention for Nationally-Recruited American Indians and Alaska Natives), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06145763 narecruitingnot on this map

Digital Smoking Cessation Intervention for Nationally-Recruited American Indians and Alaska Natives: A Full-Scale Randomized Controlled Trial (IndigeQuit)

TypeinterventionalSponsorFred Hutchinson Cancer CenterRan2025 to 2028Enrolled776ConditionsCigarette Smoking-Related CarcinomaArmsBiospecimen Collection, Smoking Cessation Intervention, Survey Administration
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jonathan B BrickerFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0000-0002-5694-8795
Margarita Santiago-TorresFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0000-0001-6051-3172
Brianna M SullivanFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0000-0002-4145-7459
Kristin E MullFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0000-0002-7918-3078
Hershel W ClarkIndigeQuit Community Advisory Board, Cancer Consortium, Seattle, WA, United States.ORCID 0009-0009-1606-2867
Camille A FogelFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0000-0001-6405-6888
Soo Bin HwangFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0009-0004-0051-4789
Alison R KeithFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0009-0005-2118-9601
Chase KornackiIndigeQuit Community Advisory Board, Cancer Consortium, Seattle, WA, United States.ORCID 0009-0007-7171-048X
Trivia Afraid Of Lightning-CraddockIndigeQuit Community Advisory Board, Cancer Consortium, Seattle, WA, United States.ORCID 0009-0003-0627-2234
Sydney A MartinezIndigeQuit Community Advisory Board, Cancer Consortium, Seattle, WA, United States.ORCID 0000-0003-1226-7506
Dean S SenecaIndigeQuit Community Advisory Board, Cancer Consortium, Seattle, WA, United States.ORCID 0009-0000-5994-3896
Crystal M StanfordIndigeQuit Community Advisory Board, Cancer Consortium, Seattle, WA, United States.ORCID 0009-0009-7233-0125
Christeine TerryFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0009-0006-7340-7217
Sierra L WilcoxIndigeQuit Community Advisory Board, Cancer Consortium, Seattle, WA, United States.ORCID 0009-0007-1044-523X
Lonnie NelsonFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0000-0001-9865-4114
Patricia Nez HendersonNavajo Nation, Window Rock, AZ, United States.ORCID 0000-0002-8087-9929

Funding

Digital smoking cessation intervention for nationally-recruited American Indians and Alaska Natives: A full-scale randomized controlled trialR01CA284687 · NCI · FRED HUTCHINSON CANCER CENTER · PI BRICKER, JONATHAN B · 2023 to 2025
$3.5M
NCI NIH HHS R01 CA284687
6 · The paper itself

Abstract

backgroundDue to the colonization of tobacco plants by European settlers and the subsequent intensive marketing of commercial tobacco products to American Indian and Alaska Native (AI/AN) communities in the United States, commercial cigarette smoking accounts for half of all deaths among AI/AN people. Limited awareness, access to treatment, and the absence of culturally relevant, effective smoking cessation interventions contribute to these high death rates.

objectiveThis study aims to culturally adapt iCanQuit, a smartphone smoking cessation app proven efficacious for the general population, for AI/AN people.

methodsA user-centered and community-based participatory research (CBPR) mixed methods approach was applied to culturally adapt iCanQuit for AI/AN people in collaboration with a community advisory board (CAB) of AI/AN individuals using a 3-step process. Step 1 identified ways to culturally adapt the iCanQuit for AI/AN people through 1-on-1 qualitative interviews with 8 prior iCanQuit AI/AN participants. Step 2 involved developing prototypes of cultural refinements identified in step 1 through regular biweekly meetings of the CAB, research, and app development teams. The prototypes were then evaluated with a separate group of 4 prior iCanQuit AI/AN participants through 1-on-1 qualitative interviews. Step 3 involved beta testing the app through a 6-day diary study followed by 1-on-1 qualitative interviews with a nationally recruited group of 7 AI/AN adults who smoke commercial cigarettes. The development work associated with step 3 was further informed by the CAB and the research and app development teams.

resultsKey findings identified 5 cultural refinements that informed subsequent app development and testing: (1) stories featuring AI/AN adults and elders emphasizing culture, spirituality, family, and community; (2) honoring the Earth as a motivator for cessation; (3) a guide character representative of AI/AN people; (4) clear distinction between ceremonial and commercial tobacco use; and (5) use of earth tones in visual design. In Step 3, all 7 (100%) diary study participants rated the beta version of the app as excellent or good/meets expectations (5/7, 71%, and 2/7, 29%, respectively) and that it felt made for them. They suggested 6 modifications which were incorporated into the final version of the app: (1) include vaping frequently asked questions, (2) feature motivation icons more prominently, (3) increase notification frequency, (4) track today's cigarettes rather than yesterday's, (5) allow users to update how much they spend per pack of cigarettes; and (6) rename the medications tool to reflect the inclusion of AI/AN traditional healing modalities.

conclusionsA user-centered and CBPR development process yielded IndigeQuit-one of the first known apps developed specifically to help AI/AN adults quit commercial cigarette smoking.

trial registrationClinicalTrials.gov NCT06145763; https://clinicaltrials.gov/ct2/show/NCT06145763.

Indexed as

American Indian or Alaska NativeIndians, North AmericanMobile ApplicationsSmoking CessationAdultCommunity-Based Participatory ResearchFemaleHumansMaleQualitative ResearchSmartphoneUnited StatesAlaska NativeAmerican Indianceremonial tobaccocommercial cigarettescultural adaptationiCanQuitIndigenousIndigeQuitNativesmartphone appssmoking cessationtailoringTribal communities

Identifiers

PMID41875428
PMCPMC13058535

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.