Evidence map›Paper›PMID 41875021›Full record

ArticleMedicine and science in sports and exercise2026

Relation between Exercise Training-Induced Changes in Oxygen Uptake Kinetics and the Power-Duration Relation.

Tze-Huan Lei, Luuk Vos, I-Lin Wang, Shunsaku Koga, Simon Marwood, Bernard Korzeniewski, Richie P Goulding

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Article in Medicine and science in sports and exercise, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tze-Huan LeiCollege of Physical Education, Hubei Normal University, Huangshi, CHINA.
Luuk VosDepartment of Biomedical Engineering and Physics, Amsterdam UMC, Amsterdam, THE NETHERLANDS.
I-Lin WangCollege of Physical Education, Hubei Normal University, Huangshi, CHINA.
Shunsaku KogaApplied Physiology Laboratory, Kobe Design University, Kobe, JAPAN.
Simon MarwoodSchool of Health & Sport Sciences, Liverpool Hope University, Liverpool, UNITED KINGDOM.
Bernard KorzeniewskiBioSimulation Center, Krakow, POLAND.
Richie P GouldingDepartment of Human Movement Sciences, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, THE NETHERLANDS.

Funding

De Nederlandse organisatie voor gezondheidsonderzoek en zorginnovatie 10091012410013
6 · The paper itself

Abstract

purposeThis study aimed to determine the relation between training-induced changes in the variable values of the power-duration relation (critical power [CP] and ) and those of pulmonary oxygen uptake ( ) kinetics (the fundamental phase time constant; , and the slow component amplitude; ).

methodsEleven healthy untrained males underwent 2 wk of severe-intensity exercise training. Before and after training, was assessed via an incremental exercise test on a cycle ergometer, CP and were assessed via constant power determination trials, and kinetics were assessed during exercise at a power output 10% above CP (posttraining at the same absolute and relative intensity as pretraining). A previously described and validated computer model of the human skeletal muscle bioenergetic system was used to provide further insight into training-induced changes.

resultsCP and were strongly inversely correlated before and after training, and their training-induced changes were also correlated. Computer simulations suggested that increased oxidative phosphorylation activity (k OX ) was the main factor determining the training-induced changes in CP and . Exercise training increased and reduced the amplitude of the , however, the training-induced changes in and were not correlated. Model simulations suggested that variations in k OX , the accessible phosphate (+creatine) pool (P acc ), and the peak inorganic phosphate (P i ) concentrations attained before task failure (Pi peak ) could explain the observed training-induced alterations in and .

conclusionsThe present study suggests that the bioenergetic mechanisms underpinning CP and are similar, whereas the relation between and appears somewhat more complex.

Indexed as

ExerciseMuscle, SkeletalOxygen ConsumptionAdultComputer SimulationEnergy MetabolismExercise TestHumansKineticsMaleOxidative PhosphorylationPhosphatesYoung AdultPhosphatesCOMPUTER MODELCRITICAL POWEREXERCISE BIOENERGETICSOXYGEN UPTAKE KINETICSPOWER-DURATION RELATION

Identifiers

PMID41875021
PMCPMC13331269

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.