Evidence map›Paper›PMID 41874807›Full record

ArticleArchives of virology2026

Identification of a novel toti-like virus symbiotic with Giardia duodenalis.

Shintaro Shichinohe, Shinji Izumiyama, Yoshihiro Takaki, Miho Hirai, Syun-Ichi Urayama, Takuro Nunoura, Makoto Kazama

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shintaro ShichinoheDepartment of Molecular Virology, Research Institute for Microbial Diseases, The University of Osaka, 3-1 Yamadaoka, Suita, Osaka, Japan. sshichi@biken.osaka-u.ac.jp.ORCID http://orcid.org/0000-0002-8783-2103
Shinji IzumiyamaDepartment of Parasitology, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.
Yoshihiro TakakiInstitute for Extra-cutting-edge Science and Technology Avant-garde Research (X-star), Japan Agency for Marine-Earth Science & Technology (JAMSTEC), Kanagawa, Japan.
Miho HiraiInstitute for Extra-cutting-edge Science and Technology Avant-garde Research (X-star), Japan Agency for Marine-Earth Science & Technology (JAMSTEC), Kanagawa, Japan.
Syun-Ichi UrayamaDepartment of Life and Environmental Sciences, Microbiology Research Center for Sustainability (MiCS), University of Tsukuba, Ibaraki, Japan.
Takuro NunouraDeep-Sea Bioresource Research Group, Research Center for Bioscience and Nanoscience (CeBN), Japan Agency for Marine-Earth Science & Technology (JAMSTEC), Kanagawa, Japan.
Makoto KazamaNEKKEN Bio-Resource Center, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Japan. kzm_makoto@nagasaki-u.ac.jp.

Funding

Japan Society for the Promotion of Science 16H06429, 16K21723, 17H05809The Joint Usage/Research Center on Tropical Disease, Institute of Tropical Medicine, Nagasaki University 2021-Ippan-35, 2022-Ippan-32, 2024-Ippan-28
6 · The paper itself

Abstract

Giardiasis is a parasitic intestinal infection of both animals and humans, caused by the enteric protozoan Giardia duodenalis (syn. G. lamblia and G. intestinalis). To date, symbiont RNA viruses of G. duodenalis: Giardia lamblia virus (GLV) and Giardia duodenalis RNA virus-2 (GdRV-2) have been reported. Here, we report the complete genome sequence of a novel virus identified in a human isolate of G. duodenalis using fragmented and primer-ligated double-stranded RNA sequencing. This virus, designated the Non-GLV Giardia duodenalis ISE strain (Noggi) virus, is genetically distinct from GLV and GdRV-2 and likely represents the third symbiont virus in Giardia parasites.

Indexed as

Giardia lambliaGiardiasisRNA VirusesAnimalsGenome, ViralHumansPhylogenyRNA, ViralSymbiosisRNA, Viral

Identifiers

PMID41874807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.