Review in Clinical reviews in allergy & immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
9 authors.
Shanshan Li *Institute of Allergy and Immunology of Shenzhen University School of Medicine, State Key Laboratory of Respiratory Disease Allergy Shenzhen University Division, Department of Respiratory and Allergy, The Third Affiliated Hospital (The Affiliated Luohu Hospital) of Shenzhen University, Shenzhen University, Shenzhen, China.ORCID http://orcid.org/0000-0003-3505-6138
Zhanling Liang *Institute of Allergy and Immunology of Shenzhen University School of Medicine, State Key Laboratory of Respiratory Disease Allergy Shenzhen University Division, Department of Respiratory and Allergy, The Third Affiliated Hospital (The Affiliated Luohu Hospital) of Shenzhen University, Shenzhen University, Shenzhen, China.ORCID http://orcid.org/0000-0002-9533-020X
Muhammad Mazhar *Institute of Allergy and Immunology of Shenzhen University School of Medicine, State Key Laboratory of Respiratory Disease Allergy Shenzhen University Division, Department of Respiratory and Allergy, The Third Affiliated Hospital (The Affiliated Luohu Hospital) of Shenzhen University, Shenzhen University, Shenzhen, China.ORCID http://orcid.org/0000-0002-3172-8737
Yun LiaoInstitute of Allergy and Immunology of Shenzhen University School of Medicine, State Key Laboratory of Respiratory Disease Allergy Shenzhen University Division, Department of Respiratory and Allergy, The Third Affiliated Hospital (The Affiliated Luohu Hospital) of Shenzhen University, Shenzhen University, Shenzhen, China.ORCID http://orcid.org/0000-0002-8151-8885
Ping-Chang YangInstitute of Allergy and Immunology of Shenzhen University School of Medicine, State Key Laboratory of Respiratory Disease Allergy Shenzhen University Division, Department of Respiratory and Allergy, The Third Affiliated Hospital (The Affiliated Luohu Hospital) of Shenzhen University, Shenzhen University, Shenzhen, China.ORCID http://orcid.org/0000-0002-6806-9464
Xiaoyu LiuInstitute of Allergy and Immunology of Shenzhen University School of Medicine, State Key Laboratory of Respiratory Disease Allergy Shenzhen University Division, Department of Respiratory and Allergy, The Third Affiliated Hospital (The Affiliated Luohu Hospital) of Shenzhen University, Shenzhen University, Shenzhen, China. lxy0901@szu.edu.cn.ORCID http://orcid.org/0000-0001-9571-3844
Xiaojun XiaoInstitute of Allergy and Immunology of Shenzhen University School of Medicine, State Key Laboratory of Respiratory Disease Allergy Shenzhen University Division, Department of Respiratory and Allergy, The Third Affiliated Hospital (The Affiliated Luohu Hospital) of Shenzhen University, Shenzhen University, Shenzhen, China. xiaojun1985918@szu.edu.cn.ORCID http://orcid.org/0000-0002-1195-0541
Funding
Medical-Engineering Interdisciplinary Research Foundation of Shenzhen University 2023YG029Open Project of State KeyLaboratory of Respiratory Disease No.SKLRD-OP-202406Science and Technology Planning Project of Guangdong Province 2023A1515012245, 2022B1515120055, 2024A1515011412Science and Technology Program of Shenzhen JCYJ20220818102005011, JCYJ20220531102217038, JCYJ20220530151215036Shenzhen Medical Research Fund A2403062The National Natural Science Foundation of China 82341060
6 · The paper itself
Abstract
The rising prevalence of food allergies has coincided with the increasing use of animal models to study disease mechanisms and potential therapeutic strategies. Animal models, particularly murine models, have been instrumental in elucidating the mechanisms of allergic sensitization, effector responses, and potential therapeutic interventions. However, despite their utility, mouse models do not fully replicate human immune responses, limiting clinical translation. This review highlights conventional inbred mouse strains, genetically modified, and humanized mouse models, focusing on commonly used strains and key experimental variables, including allergen sources, adjuvants, and sensitization routes. Evaluation methods including anaphylaxis scoring, immunological profiling and histological analysis, ensure model reliability. Advances such as genetic modifications, humanized immune components, and multi-omics approaches aim to improve model relevance, facilitating better translation to clinical applications.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Mouse Models of Food Allergies: Where Do They Take Us? · full record | OpenQuestion