Evidence map›Paper›PMID 41874489›Full record

ArticleJACC. Case reports2026

Reversible Complete Atrioventricular Block Due to Rupture of the Left Coronary Aortic Sinus.

Ken Kawase, Kenzaburo Nakajima, Yuichiro Miyazaki, Shumpei Mori, Taizo Masuda, Hiroki Horinouchi, Takeshi Kitai, Tetsuya Fukuda, Kengo Kusano

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ken KawaseDivision of Arrhythmia, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan; Department of Advanced Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Kenzaburo NakajimaDivision of Arrhythmia, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan. Electronic address: kenzabunakajima@gmail.com.
Yuichiro MiyazakiDavid Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA.
Shumpei MoriDavid Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA.
Taizo MasudaDepartment of Clinical Laboratory, National Cerebral and Cardiovascular Center, Suita, Japan.
Hiroki HorinouchiDepartment of Radiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Takeshi KitaiDepartment of Heart Failure and Transplantation, National Cerebral and Cardiovascular Center, Suita, Japan.
Tetsuya FukudaDepartment of Radiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Kengo KusanoDivision of Arrhythmia, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan; Department of Advanced Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRupture of the left coronary aortic sinus complicated by conduction disturbances has not been reported. CASE SUMMARY: An 85-year-old woman presented with chest and back pain and a complete atrioventricular block, which led to low-output syndrome. Imaging revealed a rupture of the left coronary aortic sinus with a pseudoaneurysm and a hematoma extending toward the central fibrous body. Conservative management was selected, and atrioventricular conduction gradually improved as the hematoma regressed. DISCUSSION: The hematoma compressed the atrioventricular node region, causing a reversible atrioventricular block. Infective endocarditis, antineutrophil cytoplasmic antibody-associated vasculitis, atherosclerosis, and localized dissection involving the sinuses of Valsalva have been discussed as potential mechanisms underlying this rare condition. TAKE-HOME MESSAGE: Spontaneous rupture of the sinuses of Valsalva and the resultant hematoma extending around the central fibrous body can cause a reversible complete atrioventricular block by mechanical compression of the atrioventricular node region.

Indexed as

complete atrioventricular blockhematomaleft coronary aortic sinuspseudoaneurysm

Identifiers

PMID41874489
PMCPMC13184861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.