Evidence map›Paper›PMID 41874344›Full record

ArticleAntimicrobial agents and chemotherapy2026

Polygenic, cell-envelope adaptations drive high-frequency daptomycin resistance in

Lara Kränkel, Janna Hauser, Jessica Slavetinsky, Alina Zinser, Annika Schmidt, Mulugeta Nega, Ahmed M A Elsherbini, Tanja Schneider, Christian Gille, Martin Schaller and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lara Kränkel *Interfaculty Institute of Microbiology and Infection Medicine, Cellular and Molecular Microbiology Division, University of Tübingen, Tübingen, Germany.
Janna Hauser *Interfaculty Institute of Microbiology and Infection Medicine, Cellular and Molecular Microbiology Division, University of Tübingen, Tübingen, Germany.
Jessica SlavetinskyInterfaculty Institute of Microbiology and Infection Medicine, Cellular and Molecular Microbiology Division, University of Tübingen, Tübingen, Germany.
Alina ZinserInterfaculty Institute of Microbiology and Infection Medicine, Cellular and Molecular Microbiology Division, University of Tübingen, Tübingen, Germany.
Annika SchmidtInterfaculty Institute of Microbiology and Infection Medicine, Cellular and Molecular Microbiology Division, University of Tübingen, Tübingen, Germany.
Mulugeta NegaMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.
Ahmed M A ElsherbiniInterfaculty Institute of Microbiology and Infection Medicine, Cellular and Molecular Microbiology Division, University of Tübingen, Tübingen, Germany.
Tanja SchneiderInstitute for Pharmaceutical Microbiology, University Hospital Bonn, Bonn, Germany.
Christian GilleDepartment of Neonatology, University Children's Hospital Tübingen, Tübingen, Germany.
Martin SchallerDepartment of Dermatology, University Hospital Tübingen, Tübingen, Germany.
Jörg FuchsPediatric Surgery and Urology, University Children´s Hospital Tübingen, Tübingen, Germany.
Andreas PeschelInterfaculty Institute of Microbiology and Infection Medicine, Cellular and Molecular Microbiology Division, University of Tübingen, Tübingen, Germany.ORCID 0000-0002-3209-8626
Christoph SlavetinskyInterfaculty Institute of Microbiology and Infection Medicine, Cellular and Molecular Microbiology Division, University of Tübingen, Tübingen, Germany.ORCID 0000-0001-5576-5906

Funding

Deutsches Zentrum für Infektionsforschung TTU 08.806European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) ESPGHAN Research GrantGerman Research Council (DFG) 390838134
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsDaptomycinNeonatal SepsisStaphylococcus capitisBacterial ProteinsCell WallDrug Resistance, BacterialHumansInfant, NewbornMicrobial Sensitivity TestsStaphylococcal InfectionsStaphylococcus aureusVancomycinAnti-Bacterial AgentsBacterial ProteinsDaptomycinVancomycinbacterial cell walldaptomycin resistanceLOSNECneonatal sepsisNRCS-AS. capitis

Identifiers

PMID41874344
PMCPMC13148029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.