ArticleInfectious disease reports2026
Post-COVID-19 Rabies Surveillance and Risk Factors in Rural Eastern Cape, South Africa: A One Health Perspective.
Article in Infectious disease reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
backgroundRabies remains a neglected zoonotic disease in South Africa, particularly in rural areas where surveillance weaknesses, behavioral gaps, and limited One Health coordination persist.
objectivesThis study assessed rabies surveillance, behavioral risk factors, and system responsiveness in two rural Eastern Cape communities, with a focus on post-pandemic resilience within a One Health framework.
methodsA cross-sectional, community-based pilot study was conducted among 109 residents using structured questionnaires to collect data on demographics, rabies awareness, vaccination practices, and service disruptions. Descriptive, bivariate, and multivariate analyses identified predictors of dog-bite exposure and pet vaccination. Machine learning models (Decision Tree and Random Forest) were applied to explore risk hierarchies. A composite Surveillance Gap Index (SGI) was developed to integrate behavioral and systemic indicators.
resultsWhile 88% of participants were aware of rabies, only 35% attended awareness campaigns. Dog-bite exposure affected 51% of households, with significantly higher risk among males (aOR = 4.33;
conclusionsIntegrating behavioral insights and predictive analytics into One Health strategies can strengthen rabies surveillance and support progress toward eliminating human rabies by 2030.
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