ArticleEuropean journal of breast health2026
Pittsburgh Classification and Treatment Algorithm for Idiopathic Granulomatous Mastitis: A Multicenter Cohort Study.
Article in European journal of breast health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Clinical Outcomes in Initial Hirudotherapy versus Standard Treatment in Idiopathic Granulomatous Mastitis: A Comparative Cohort Study.European journal of breast health · 2026Article
- Oxidative Stress-Related DNA Damage in Patients with Idiopathic Granulomatous Mastitis: A Prospective Case-Control Study.Journal of clinical medicine · 2026Article
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8 authors.
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Abstract
Objective: Idiopathic granulomatous mastitis (IGM) is a rare inflammatory breast condition lacking standardized treatment and with unpredictable outcomes. To address these issues, using clinical and ultrasound findings from an initial subset, we created the Pittsburgh Classification to stratify severity and developed a corresponding treatment algorithm for IGM, then evaluated its effectiveness in a larger cohort of IGM patients. Materials and Methods: This retrospective multicenter study reviewed clinical and sonographic findings and outcomes of women with biopsy-proven IGM treated at multiple breast centers between 2020 and 2025. The Pittsburgh clinical classification ranges from Type 1 (minimal skin irritation) to Type 5 (widespread involvement); ultrasound classification spans Type A (localized mass ≤2 cm) to Type D (diffuse disease). Treatments were assessed utilizing the Pittsburgh algorithm, with responses classified as full response (CR), near-complete response (nCR), or no response (NR). Chi-square tests assessed associations ( Results: Of 522 patients included (mean age 37.0±8.8 years), 86.4% ( Conclusion: Concordance with the proposed IGM treatment algorithm based on clinical and ultrasound findings resulted in significantly higher CR rates. Multiple foci and stratified clinical types correlated with outcomes. Prospective global research is needed to validate these findings.
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