Evidence map›Paper›PMID 41873989›Full record

ArticleEpidemiologia (Basel, Switzerland)2026

Vitamin D Serum Status and Associated Factors Among Women with Cervical Lesions.

Zinhle Simelane, Likhona S Masika, Charles B Businge, Zizipho Z A Mbulawa

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In one paragraph

Article in Epidemiologia (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Zinhle SimelaneDepartment of Laboratory Medicine and Pathology, Walter Sisulu University, Mthatha 5100, South Africa.
Likhona S MasikaDepartment of Laboratory Medicine and Pathology, Walter Sisulu University, Mthatha 5100, South Africa.
Charles B BusingeDepartment of Obstetrics and Gynaecology, Walter Sisulu University, Mthatha 5100, South Africa.ORCID 0000-0002-8393-1198
Zizipho Z A MbulawaDepartment of Laboratory Medicine and Pathology, Walter Sisulu University, Mthatha 5100, South Africa.ORCID 0000-0001-9073-4777

Funding

National Research Foundation NRF Rating IncentivesNational Research Foundation Postgraduate BursarySouth African Medical Research Council Research Capacity Development Initiative
6 · The paper itself

Abstract

BACKGROUND/

objectivesVitamin D plays a role in cellular regulation and immune processes relevant to cervical carcinogenesis, yet data on vitamin D status and its determinants in high-burden settings such as South Africa remain scarce. This paper therefore describes the prevalence of vitamin D deficiency, insufficiency, and sufficiency, and explores associated factors among women with cervical lesions.

methodsA descriptive cross-sectional study was conducted among 103 women aged 18-81 years. Women were referred to Nelson Mandela Academic Hospital due to cervical cancer, high-grade squamous intraepithelial lesions (HSILs), or atypical squamous cells-cannot exclude HSIL, or low-grade squamous intraepithelial lesions, or atypical squamous cells of undetermined significance. The total serum 25(OH)D (D

resultsVitamin D insufficiency was observed in 46.60% of participants and deficiency in 26.21% while only 27.18% had sufficient levels. Overall, vitamin D deficiency or insufficiency was more common than sufficiency (72.82%; 27.18%,

conclusionsVitamin D deficiency and insufficiency were common among women with cervical lesions in this rural South African population. Associations with BMI suggest context-specific influences on vitamin D status. Owing to the study's cross-sectional design and lack of normal cervical cytology participants, the findings are descriptive and exploratory, underscoring the need for longitudinal and comparative research to better define the role of vitamin D in cervical disease.

Indexed as

abnormal cervixbody mass indexhuman immunodeficiency virusserum vitamin Dwomen

Identifiers

PMID41873989
PMCPMC13010710

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