Evidence map›Paper›PMID 41873979›Full record

ArticleSexually transmitted diseases2026

Prevalence of and Factors Associated With Urethral and Rectal STIs Among a Cross-Sectional Sample Men Who Have Sex With Men.

Felix Ochieng, Patriciah Wambua, Joshua Kimani, Mary Wanjiru, Walter Agingu, Rhoda Kabuti, Nontlantla Mdletshe, Lyle R McKinnon, Fredrick O Otieno, Supriya D Mehta

Abstract read
In one paragraph

Article in Sexually transmitted diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Felix OchiengFrom the Nyanza Reproductive Health Society, Kisumu, Kenya.
Patriciah WambuaFrom the Nyanza Reproductive Health Society, Kisumu, Kenya.
Joshua KimaniPartners for Health and Development in Africa, Nairobi, Kenya.
Mary WanjiruPartners for Health and Development in Africa, Nairobi, Kenya.
Walter AginguFrom the Nyanza Reproductive Health Society, Kisumu, Kenya.
Rhoda KabutiPartners for Health and Development in Africa, Nairobi, Kenya.
Nontlantla MdletsheDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Lyle R McKinnonDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Fredrick O OtienoFrom the Nyanza Reproductive Health Society, Kisumu, Kenya.
Supriya D MehtaDivision of Infectious Diseases, Department of Medicine, Rush University Medical College, Chicago, IL.

Funding

The Clinical History of Rectal and Urethral STIs among MSM: characterizing microbiome host immune interactions for diagnostic and vaccine advancesR01AI177005 · NIAID · RUSH UNIVERSITY MEDICAL CENTER · PI Lyle Robert McKinnon, Supriya Dinesh Mehta · 2023 to 2026
$2.5M
NIAID NIH HHS R01 AI177005
6 · The paper itself

Abstract

backgroundWe examined the prevalence and factors associated with sexually transmitted infections (STIs) among men who have sex with men (MSM) in Kenya.

methodsA cross-sectional analysis was conducted using baseline data from the Mbili Pamoja cohort study, which enrolled 501 MSM (250 in Kisumu and 251 in Nairobi) aged 18 to 39 y between June and November 2024. Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) were detected in urine and clinician-collected rectal swabs. Multivariable logistic regression was used to identify factors associated with urethral and rectal CT/NG.

resultsThe prevalence of urethral CT and/or NG infections was 9.2% in Kisumu and 3.7% in Nairobi; rectal CT and/or NG prevalence was 10.4% in Kisumu and 18.7% in Nairobi. In multivariable analysis, urethral CT/NG was more common among MSM aged 25 to 29 y versus 18 to 24 y, last sex partner being a cisgender woman, and identifying as transgender or nonbinary. Hazardous drug use was inversely associated with urethral STIs. Rectal STIs were increased for participants reporting receptive or versatile sexual role, group sex, being transgender/nonbinary, and elevated depressive symptoms. Hazardous alcohol use, food insecurity, and recent antibiotic use were inversely associated with rectal infections. Self-reported dysuria and penile discharge showed low sensitivity (38.6% and 30.6%, respectively) and high specificity (>80%) for urethral infections. Rectal symptoms were infrequently reported but showed moderate sensitivity and high specificity.

conclusionsMSM in Kisumu and Nairobi have a substantial burden of frequently asymptomatic urethral and rectal CT and NG infections. While some modifiable sexual exposures were identified, results also highlight the need for integrated mental health and substance use services.

Indexed as

Chlamydia InfectionsGonorrheaHomosexuality, MaleRectal DiseasesSexually Transmitted DiseasesUrethral DiseasesAdolescentAdultChlamydia trachomatisCross-Sectional StudiesHumansKenyaMaleNeisseria gonorrhoeaePrevalenceRectum

Identifiers

PMID41873979
PMCPMC13150786

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