Evidence map›Paper›PMID 41873943›Full record

ArticleeLife2026

The 1000

Adam L Kenet, Sooraj Achar, Alka Dwivedi, John Buckley, Marie Pouzolles, Haying Qin, Christopher Chien, Naomi Taylor, Grégoire Y Altan-Bonnet

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Adam L Kenet *Immunodynamics Group, Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
Sooraj Achar *Immunodynamics Group, Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
Alka DwivediPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
John BuckleyPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
Marie PouzollesPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
Haying QinPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
Christopher ChienPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
Naomi TaylorPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
Grégoire Y Altan-BonnetImmunodynamics Group, Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, United States.ORCID https://orcid.org/0000-0002-9602-8133

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preclinical studies of chimeric antigen receptor (CAR)-T cell immunotherapies are often based on monitoring bioluminescent tumors implanted in mice to assess anti-tumor cytotoxicity. Here, we introduce maRQup (

Indexed as

ImmunotherapyNeoplasmsAnimalsDisease Models, AnimalHumansLuminescent MeasurementsMiceReceptors, Chimeric AntigenT-LymphocytesReceptors, Chimeric Antigenbioluminescent image processingcancer biologyCAR-T cellsimmunologyinflammationmathematical modelingmouse

Identifiers

PMID41873943
PMCPMC13012723

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.