ReviewJournal of cell science2026
The roles of the microtubule cytoskeletal network in cardiac mechanobiology.
Review in Journal of cell science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mechanical regulation of LINC complex function: structural basis, physiological roles, and disease mechanisms in transnuclear mechanotransduction.Frontiers in cell and developmental biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The intracellular cytoskeletal network is a central mediator of mechanobiology, transmitting extracellular cues from the cell membrane to elicit downstream changes in cell behaviour and morphology. In cardiomyocytes, mechanotransduction via the intracellular cytoskeleton plays a pivotal role in regulating cardiac output, development and pathological remodelling. Various structural components contribute to this process, including tension-mediated ion channels, contractile sarcomere units, transmembrane cell junction proteins, intermediate filaments and the microtubule network. Among these components, microtubules are the largest and most rigid cytoskeletal elements. This Review highlights the essential, but often understated, role of microtubules in cardiomyocyte mechanobiology, particularly in their coordination with other cytoskeletal elements. Furthermore, this Review highlights how the microtubule cytoskeletal network is connected to cardiac disease phenotypes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.