Evidence map›Paper›PMID 41873648›Full record

SynthesisJournal of cosmetic dermatology2026

Cross-Cultural Beliefs and Stigmatization in Vitiligo: A Systematic Review.

Sophia Ma, Tarek Zieneldien, Isabella J Tan, Mohammad Jafferany

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sophia MaSchool of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Tarek ZieneldienSchool of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-0230-4951
Isabella J TanRobert Wood Johnson Medical School, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.ORCID https://orcid.org/0000-0002-5756-6609
Mohammad JafferanyDepartment of Psychiatry and Behavioral Sciences, Central Michigan University College of Medicine, Mount Pleasant, Michigan, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitiligo is an autoimmune condition marked by depigmentation of the skin and is frequently associated with psychosocial distress. Although often dismissed as cosmetic, vitiligo carries a substantial burden influenced by cultural beliefs, stigma, and access to medical education.

aimsThis review aims to examine the literature on cross-cultural beliefs, stigmatization, psychological comorbidities, and quality of life (QoL) outcomes in individuals with vitiligo.

methodsA comprehensive search of PubMed, Embase, and PsycINFO was conducted to identify peer-reviewed studies discussing cultural beliefs, stigma, psychological burden, or QoL in individuals with vitiligo. Inclusion criteria encompassed original studies in English assessing relevant psychosocial or cultural domains.

resultsTwenty-three studies met inclusion criteria. Cultural attributions of vitiligo varied widely, with some populations linking the disease to contagion, divine punishment, or supernatural causes. These beliefs were more prevalent in regions with lower health literacy and limited access to dermatologic care. Stigmatization-manifesting as social exclusion, employment and marital discrimination, and internalized shame-was consistently reported across settings, though more severe in female patients and individuals with darker skin phototypes in certain regions. QoL impairment was greater in African, Middle Eastern, and South Asian populations compared to Western cohorts. Coping strategies included concealment, spiritual reliance, and use of complementary and alternative medicine (CAM).

conclusionVitiligo imposes a global psychosocial burden that is amplified by cultural misconceptions and stigma. Culturally tailored, multidisciplinary interventions-including education, psychological support, and community-based stigma reduction-are crucial to improving outcomes. Future research should focus on high-stigma, underrepresented populations to inform equitable care.

Indexed as

Cross-Cultural ComparisonSocial StigmaStereotypingVitiligoHumansQuality of Lifecross‐cultural beliefscultural perceptionspsychodermatologypsychosocial distressquality of lifestigmatizationvitiligo

Identifiers

PMID41873648
PMCPMC13010235

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.