Evidence map›Paper›PMID 41873609›Full record

ArticleOrganic letters2026

Remote Stereocontrol in Aryl/Alkyl C-H Insertion Reactions of Rhodium Carbenes: Assembly of Pseudorigidols A and B.

Linda Ung, Sarah N Dishman, Sophia Zhang, James C Fettinger, Jared T Shaw

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linda UngDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, California 95616, United States.
Sarah N DishmanDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, California 95616, United States.
Sophia ZhangDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, California 95616, United States.ORCID 0009-0005-0771-1985
James C FettingerDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, California 95616, United States.ORCID 0000-0002-6428-4909
Jared T ShawDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, California 95616, United States.ORCID 0000-0001-5190-493X

Funding

Supplement: Studies in the Synthesis of Complex Organic Molecules with Donor-Donor CarbenesR35GM149209 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Jared Thomas Shaw · 2023 to 2026
$1.8M
NIGMS NIH HHS R35 GM149209
6 · The paper itself

Abstract

The first total syntheses of pseudorigidols A and B are reported. Our syntheses employ a rhodium-catalyzed C-H insertion reaction to build the tricyclic core. The catalyst screen revealed the influence of a remote stereogenic center on the diastereoselectivity of the insertion. Using two different catalysts, we were able to synthesize the two natural products with high diastereoselectivity. These results will lay the foundation for further studies on the influence of remote stereogenic centers.

Identifiers

PMID41873609
PMCPMC13105247

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.