ReviewSmall (Weinheim an der Bergstrasse, Germany)2026
Interfacial Chemistry-Tailored Silica&Metal-Based Heterostructures: from Rational Design to Antibacterial Applications.
Review in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The escalating global crisis of antimicrobial resistance urgently demands innovative antimicrobial agents beyond conventional antibiotics. Metal-based nanomaterials, including metal/metal oxide nanoparticles (NPs) and metal-organic frameworks (MOFs), represent a promising class of broad-spectrum antibacterial agents. However, their practical application is often hindered by intrinsic limitations such as aggregation, instability, and cytotoxicity. Integrating them with structurally and chemically tunable silica nanoparticles has been demonstrated as a promising strategy to mitigate the limitations and engineer advanced nanohybrids with synergistic functionalities. This review highlights how tailored interfacial chemistry achieves precise architectural control over silica&metal-based nanohybrids. The controlled nanoarchitecture is essential to fully exploit the structural and functional contributions of silica components to overcome the physiochemical limitations of meta-based material. We then examine the biological performance of these heterostructures mainly in antibacterial fields, including membrane disruption, stimuli-responsive activation, biofilm penetration/eradication, and receptor-mediated active targeting to pathogenic bacteria. Finally, challenges and future research directions are outlined based on our own perspectives, providing a design framework for next-generation antimicrobial nanotherapeutics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.