Evidence map›Paper›PMID 41873570›Full record

ReviewBJS open2025

Importance of early postoperative mobilization: comprehensive review.

Abdulaziz Alsuwaylihi, Dominic O'Connor, Girish P Joshi, Henrik Kehlet, Dileep N Lobo

Abstract readReview
In one paragraph

Review in BJS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abdulaziz AlsuwaylihiNottingham Digestive Diseases Centre, Division of Translational Medical Sciences, School of Medicine, University of Nottingham, Queen's Medical Centre, Nottingham, UK.ORCID 0000-0003-1737-4538
Dominic O'ConnorSchool of Health Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.ORCID 0000-0002-3054-0636
Girish P JoshiDepartment of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Henrik KehletSection for Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.ORCID 0000-0002-2209-1711
Dileep N LoboNottingham Digestive Diseases Centre, Division of Translational Medical Sciences, School of Medicine, University of Nottingham, Queen's Medical Centre, Nottingham, UK.ORCID 0000-0003-1187-5796

Funding

Arthritis Research UK 19891Medical Research Council MR/K00414X/1Ministry of Education of Saudi Arabia A948ZTNIHR Nottingham Biomedical Research Centre NIHR203310
6 · The paper itself

Abstract

backgroundEarly postoperative mobilization is an important component of enhanced recovery after surgery protocols, which aim to improve postoperative outcomes. This narrative review explores the historical evolution, physiological impact, and clinical advantages of early postoperative mobilization.

methodsThe Embase, MEDLINE, and PubMed databases were searched, without time restrictions, for studies related to postoperative immobilization and mobilization. Randomized clinical trials, observational studies, systematic reviews, meta-analyses, and clinical guidelines pertaining to adult surgical patients were reviewed, aiming to summarize the historical background, the pathophysiology of immobilization, the clinical outcomes of early postoperative mobilization, anaesthetic aspects, adverse events, limitations of the current evidence, and key barriers.

resultsExtended postoperative immobilization was consistently linked with negative physiological outcomes, including muscle atrophy, insulin resistance, venous thromboembolism, and postoperative pulmonary complications. Several studies indicated that each additional day of postoperative bed rest was associated with a nearly threefold increase in the risk of postoperative pulmonary complications, and remaining on bed rest for more than 3 days was associated with a 2.7-fold higher risk of postoperative pneumonia. Conversely, early postoperative mobilization was associated with shorter hospital length of stay, with reductions of up to 34% reported in some surgical populations, and improved functional recovery. However, the effects of early postoperative mobilization on morbidity, quality of life, and mortality were inconsistent across studies.

conclusionsEarly postoperative mobilization provides significant functional and physiological advantages. However, the strength of evidence supporting its impact on clinical outcomes varies according to surgical subspecialities. To improve implementation and reinforce evidence-based recommendations, future research should focus on standardized definitions of early postoperative mobilization, consistent outcome measures, and higher-quality, subspeciality-specific studies.

Indexed as

Early AmbulationPostoperative CarePostoperative ComplicationsBed RestHumansLength of StayQuality of Lifeambulationbarriersenablersenhanced recovery after surgerypathophysiologyperioperative care

Identifiers

PMID41873570
PMCPMC13010080

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.