Evidence map›Paper›PMID 41873428›Full record

Trial reportPeerJ2026

The effects of remimazolam on emergence agitation in patients undergoing nasal surgery: a clinical randomized controlled trial.

Xuelei Zhou, Xianchun Liu, Linlin Chen, Li Zhao, Wei Mao, Longyi Zhang, Ying Xie, Linji Li

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xuelei Zhou *Department of Anesthesiology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.
Xianchun Liu *Department of Anesthesiology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.
Linlin ChenDepartment of Anesthesiology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.
Li ZhaoDepartment of Anesthesiology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.
Wei MaoDepartment of Anesthesiology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.
Longyi ZhangDepartment of Anesthesiology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.
Ying XieDepartment of Anesthesiology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.
Linji LiDepartment of Anesthesiology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Emergence Agitation (EA) is a common postoperative complication, particularly prevalent following nasal surgeries. The occurrence of EA not only elevates the risk of self-inflicted injuries or harm to others but may also lead to a series of severe postoperative complications. This study aims to evaluate the effect of remimazolam on EA in patients undergoing nasal surgery and compare its efficacy with that of conventional anesthetic agents. Materials and methods: This randomized controlled trial included 100 patients undergoing elective nasal surgery under general anesthesia from June to September 2024. Patients were randomly assigned (1:1) to the R group (remimazolam) or the C group (propofol). Agitation levels were measured using Riker Sedation-Agitation Scale (SAS), recording each patient's highest score. The primary outcome was the incidence of EA, with secondary outcomes including hemodynamic parameters, emergence time, and adverse events. Results: The results indicated that the incidence of EA was significantly lower in the R group compared to the C group (22% Conclusions: Remimazolam holds significant clinical application value and potential in surgeries with a high incidence of EA.

Indexed as

Emergence DeliriumHypnotics and SedativesNasal Surgical ProceduresPostoperative ComplicationsAdultAnesthesia, GeneralAnesthesia Recovery PeriodFemaleHumansIncidenceMaleMiddle AgedPropofolHypnotics and SedativesPropofolAdverse effectsEmergence agitationNasal surgeryPropofolRemimazolam

Identifiers

PMID41873428
PMCPMC13006008

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.