Trial reportDrug design, development and therapy2026
Effects of Ropivacaine-Based Thoracic Paravertebral Block versus Erector Spinae Plane Block on Quality of Recovery in Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Trial.
Trial report in Drug design, development and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of Adding Erector Spinae Plane Block to a Multimodal Analgesic Regimen on Quality of Recovery After Laparoscopic Colon Cancer Surgery: A Prospective Randomized Controlled Trial.Journal of pain research · 2026Trial
- Is Thoracic Paravertebral Block Truly Superior to Erector Spinae Plane Block? Re-Evaluating the Evidence from a Recovery Perspective [Letter].Drug design, development and therapy · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Colorectal cancer remains a leading cause of cancer-related mortality worldwide. Postoperative pain can impair recovery. Thoracic paravertebral block (TPVB) and erector spinae plane block (ESPB) are regional analgesic techniques that may enhance recovery, but their comparative efficacy in colorectal surgery is not well established. This study aimed to compare the effects of TPVB and ESPB on the quality of recovery in patients undergoing colorectal cancer surgery. Methods: In this single-center, single-blind, randomized controlled trial, 87 patients scheduled for elective laparoscopic colorectal cancer surgery were initially enrolled and randomly assigned. Ultimately, 85 patients were included in the per-protocol analysis, distributed as follows: the bilateral TPVB (n = 29), the bilateral ESPB (n = 28), and the control (n = 28). Both blocks were performed at the T10 level using 20 mL of 0.375% ropivacaine per side. The primary outcome was the Quality of Recovery-15 (QoR-15) scores at 24 hours postoperatively. Secondary outcomes included pain scores, overall benefit of analgesia scores (OBAS), area under the curve (AUC) analyses for these scores and opioid consumption. Results: Both TPVB and ESPB groups had higher QoR-15 scores at 24 hours compared to controls (TPVB: 122.03 ± 4.00, ESPB: 119.00 ± 3.09, Control: 109.79 ± 2.89; both Conclusion: Both TPVB and ESPB improve recovery quality and analgesia after laparoscopic colorectal cancer surgery. Overall, the two block techniques provided comparable benefits for postoperative recovery and analgesia. Trial Registration: ChiCTR2400089500.
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