Evidence map›Paper›PMID 41873332›Full record

ArticleDiscovery immunology2026

Immunity to helminths in complex environments: co-infection disrupts effective granuloma formation and parasite clearance.

Breton Fougere, Anupama Ariyaratne, Naomi Chege, Shashini Perera, Emma Forrester, Jyrus Capara, Aralia Leon Coria, Mayara de Cassia Luzzi, Joel Bowron, Edina K Szabo and 1 more

Abstract read
In one paragraph

Article in Discovery immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Breton FougereDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Anupama AriyaratneDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Naomi ChegeDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Shashini PereraDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Emma ForresterDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Jyrus CaparaDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Aralia Leon CoriaDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Mayara de Cassia LuzziDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Joel BowronDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Edina K SzaboDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Constance A M FinneyDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-8459-8462

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The intestinal roundworm Methods and Results: We used flow cytometry and immunofluorescence to show that granulomas in trickle-infected female mice contain elevated levels of IgG Conclusion: Together, these findings highlight the importance of local immune responses to tissue-invading worms and help explain why helminth elimination is frequently more difficult in the complex immune environments found in field settings compared with laboratory conditions.

Indexed as

co-infectiongranulomaHeligmosomoidesToxoplasmatrickle infection

Identifiers

PMID41873332
PMCPMC13006141

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.