Evidence map›Paper›PMID 41873191›Full record

ArticleACR open rheumatology2026

Herpes Zoster Vaccine Uptake Among United States Adults With Rheumatic Disease: A Mixed-Methods Analysis.

Justin Carrico, Catherine McGuiness, Marie Yasuda, Chi-Chang Chen, Vasudha Gupta, Rita Campos, Nikita Stempniewicz, Justin Gatwood

Abstract read
In one paragraph

Article in ACR open rheumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Justin CarricoGSK, Philadelphia, Pennsylvania.
Catherine McGuinessIQVIA, Wayne, Pennsylvania.
Marie YasudaIQVIA, Wayne, Pennsylvania.
Chi-Chang ChenIQVIA, Wayne, Pennsylvania.
Vasudha GuptaIQVIA, Wayne, Pennsylvania.
Rita CamposGSK, Philadelphia, Pennsylvania.
Nikita StempniewiczGSK, Philadelphia, Pennsylvania.
Justin GatwoodGSK, Philadelphia, Pennsylvania.ORCID https://orcid.org/0000-0002-4801-8555

Funding

GSK VEO-000679
6 · The paper itself

Abstract

objectiveAdults with rheumatic diseases are at increased risk for herpes zoster (HZ). Recommendations for the recombinant zoster vaccine (RZV) were expanded in 2021 to include those aged ≥19 years at increased risk for HZ due to immunodeficiency or immunosuppression because of disease or therapy, but the impact of these expanded recommendations is unclear. This study assessed the impact of the updated recommendations on RZV uptake among adults with rheumatic disease in the US.

methodsA retrospective cohort analysis used open-source claims data to estimate RZV uptake, series completion, and dosing schedule compliance among unvaccinated adults with rheumatic disease from October 2021 to June 2023. Interviews with rheumatologists were conducted and thematically analyzed to characterize RZV vaccination practices related to managing patients with rheumatic disease.

resultsRZV uptake among adults with rheumatic disease and without prior RZV over the 20-month period following the updated recommendations was gradual (7.0%-10.4% across conditions) and low, and was particularly less likely among adults <50 years of age. The odds of RZV uptake were higher among those of older age, those with a household income greater than or equal to $50,000, and those of a non-White race or ethnicity. Financial concerns, lack of formal processes for tracking vaccination records and delivering reminders, and insufficient education and awareness were key barriers to RZV vaccination according to rheumatologists.

conclusionRZV uptake among adults with rheumatic disease has gradually increased, and opportunities to improve HZ prevention exist, some of which may be addressed through targeted educational efforts.

Identifiers

PMID41873191
PMCPMC13093380

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