Evidence map›Paper›PMID 41873119›Full record

ArticleImmunity, inflammation and disease2026

Correlation Between SII and Lymphocyte Subsets in Gastric Cancer Patients and Its Prognostic Importance.

Xi Yan, Yinghao Niu, Jing Du, Gang Lu, Yiyang Guo, Jinyan Zhang, Yanyan Du, Xingxiao Yang, Ming Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunity, inflammation and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Xi YanDepartment of Clinical Laboratory, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yinghao NiuDepartment of Clinical Biobank, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jing DuSchool of Medical Technologies, Hebei Medical University, Shijiazhuang, Hebei, China.
Gang LuDepartment of Clinical Laboratory, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yiyang GuoDepartment of Clinical Laboratory, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jinyan ZhangDepartment of Clinical Laboratory, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yanyan DuDepartment of Clinical Laboratory, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Xingxiao YangDepartment of Hospital Infection Management, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Ming MaDepartment of Clinical Laboratory, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.ORCID https://orcid.org/0009-0004-9293-5264

Funding

Government-funded Clinical Medicine Outstanding Talent Training Program ZF2025220Hebei Natural Science Foundation H2020206292Hebei Science and Technology Program 22377791DMedical Science Research Project of Hebei 20241554
6 · The paper itself

Abstract

purposeThis study aims to investigate the correlation and clinical significance of the systemic immune-inflammation index (SII), which reflects the inflammatory state, with lymphocyte subsets representing the immune system.

methodsThe clinical-pathological and laboratory data of 95 patients with gastric cancer and 44 healthy controls were retrospectively analyzed in this study. The relationship between SII and clinicopathological characteristics, lymphocyte subsets, and other indicators was assessed through the Chi-square test and Spearman correlation analysis. Kaplan-Meier curves, log-rank test, and Cox regression were used for survival analysis.

resultsCompared with the control group, gastric cancer patients have higher SII (p < 0.01) and lower CD3

conclusionSII in gastric cancer patients exhibits the strongest correlation with CD4

Indexed as

InflammationLymphocyte SubsetsStomach NeoplasmsAdultAgedFemaleHumansLymphocyte CountMaleMiddle AgedNeoplasm StagingPrognosisRetrospective Studiesbiomarkergastric cancerlymphocyte subsetsprognosissystemic immune‐inflammation index

Identifiers

PMID41873119
PMCPMC13097496

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.