Evidence map›Paper›PMID 41873039›Full record

ArticleBiomacromolecules2026

Investigation of Antitumor Activity of Modified Citrus Pectin: Oral and Intravenous Administration Assessed via Molecular Imaging.

Fábio Fernando Alves da Silva, Sofia Nascimento Dos Santos, Lucas de Freitas Pedrosa, Vinicius Gonçalves Rodrigues, Jonathas Xavier Pereira, Jhonatas Pedrosa Marim Pereira, Dino Seigo Gushiken Junior, Thiécla Katiane Osvaldt Rosales, Luís Alberto Pereira Dias, Patrick Jack Spencer and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fábio Fernando Alves da SilvaCentro de Radiofarmácia, Comissão Nacional de Energia Nuclear, Instituto de Pesquisas Energéticas e Nucleares, São Paulo, São Paulo 05508-000, Brasil.ORCID 0009-0002-6502-9317
Sofia Nascimento Dos SantosSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, U.K.
Lucas de Freitas PedrosaDepartment of Food Science and Experimental Nutrition, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, São Paulo 05508-900, Brazil.
Vinicius Gonçalves RodriguesInstituto de Patologia Tropical e Saúde Pública (IPTSP), Universidade Federal de Goiás (UFG), Goiânia, Goiás 74605-050, Brasil.
Jonathas Xavier PereiraInstituto de Patologia Tropical e Saúde Pública (IPTSP), Universidade Federal de Goiás (UFG), Goiânia, Goiás 74605-050, Brasil.
Jhonatas Pedrosa Marim PereiraCentro de Radiofarmácia, Comissão Nacional de Energia Nuclear, Instituto de Pesquisas Energéticas e Nucleares, São Paulo, São Paulo 05508-000, Brasil.
Dino Seigo Gushiken JuniorCentro de Biotecnologia, Comissão Nacional de Energia Nuclear, Instituto de Pesquisas Energéticas e Nucleares, São Paulo, São Paulo 05508-000, Brasil.
Thiécla Katiane Osvaldt RosalesDepartment of Food Science and Experimental Nutrition, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, São Paulo 05508-900, Brazil.
Luís Alberto Pereira DiasCentro de Radiofarmácia, Comissão Nacional de Energia Nuclear, Instituto de Pesquisas Energéticas e Nucleares, São Paulo, São Paulo 05508-000, Brasil.
Patrick Jack SpencerCentro de Biotecnologia, Comissão Nacional de Energia Nuclear, Instituto de Pesquisas Energéticas e Nucleares, São Paulo, São Paulo 05508-000, Brasil.
João Paulo FabiDepartment of Food Science and Experimental Nutrition, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, São Paulo 05508-900, Brazil.ORCID 0000-0002-7430-7756
Emerson Soares BernardesCentro de Radiofarmácia, Comissão Nacional de Energia Nuclear, Instituto de Pesquisas Energéticas e Nucleares, São Paulo, São Paulo 05508-000, Brasil.ORCID 0000-0002-0029-7313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study employed molecular imaging to evaluate MCP (PectaSol-C, modified citrus pectin, a complex polysaccharide with antitumor potential) absorption and pharmacokinetics following oral and intravenous (IV) administration. MCP was radiolabeled with technetium-99m (

Indexed as

Antineoplastic AgentsMolecular ImagingPectinsAdministration, IntravenousAdministration, OralAnimalsCell Line, TumorFemaleGalectin 3HumansMiceMice, KnockoutTechnetiumTissue DistributionAntineoplastic Agentscitrus pectinGalectin 3PectinsTechnetium

Identifiers

PMID41873039
PMCPMC13080965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.