Evidence map›Paper›PMID 41872979›Full record

ArticlePhysiological reports2026

Psychophysical stress during a 24 h dive: A case study of an older male diver.

Alessandra Barassi, Andrea Brizzolari, Federico Rubino, Anna Caretti, Federica Nenna, Murat Egi, Daniela Caldirola, Alessandra Alciati, Giampaolo Perna, Silvia Daccò and 2 more

Abstract read
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alessandra BarassiDepartment of Health Sciences, Università Degli Studi of Milan, Milan, Italy.
Andrea BrizzolariDepartment of Health Sciences, Università Degli Studi of Milan, Milan, Italy.
Federico RubinoDepartment of Health Sciences, Università Degli Studi of Milan, Milan, Italy.ORCID https://orcid.org/0000-0001-9620-1883
Anna CarettiDepartment of Health Sciences, Università Degli Studi of Milan, Milan, Italy.
Federica NennaDepartment of General Psychology, University of Padua, Padua, Italy.
Murat EgiComputer Engineering Department, Galatasaray University, Istanbul, Turkey.
Daniela CaldirolaDepartment of Biomedical Sciences, Humanitas University, Como, Italy.
Alessandra AlciatiHumanitas, Clinical and Research Center, IRCCS, Milan, Italy.
Giampaolo PernaHumanitas, Clinical and Research Center, IRCCS, Milan, Italy.
Silvia DaccòDepartment of Biomedical Sciences, Humanitas University, Como, Italy.
Lara Alessia MoltaniComftech Srl, Monza, Italy.ORCID https://orcid.org/0009-0000-2495-3330
Danilo CialoniDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0001-7655-1261

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case study investigated the psychophysiological stress responses of a diver during and after a 24-h hyperbaric exposure. Comprehensive biomarker analysis revealed relevant changes in oxidative stress parameters and cardiac muscle markers. Notably, a critical time point at 6 h (T2) emerged, characterized by peak oxidative stress and diminished antioxidant capacity, followed by progressive cardiac strain as evidenced by elevated creatine kinase isoenzime (CK-MBm) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) levels. Despite these physiological challenges, no pathological tissue damage was detected, indicating effective endogenous defense mechanisms. Moreover, no significant psychophysiological symptoms were detected before, during, and after the dive, except for tiredness and insomnia. Cognitive assessments reflected adaptive shifts in response strategies under prolonged stress, emphasizing the importance of monitoring to prevent operational risks. These findings highlight the need to consider dive duration carefully, suggesting that introducing rest intervals or personnel rotation around the critical T2 threshold may mitigate physiological fatigue and optimize performance. This study provides valuable insights into human adaptation to extended hyperbaric conditions and informs safety protocols for commercial and military diving operations.

Indexed as

DivingDiving and Hyperbaric MedicineStress, PhysiologicalAgedBiomarkersHumansMaleNatriuretic Peptide, BrainOxidative StressPeptide FragmentsBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)cognitive testnitric oxideNT‐proBNPoxidative stressscuba diving

Identifiers

PMID41872979
PMCPMC13098038

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.