Evidence map›Paper›PMID 41872960›Full record

ArticleMolecular plant pathology2026

RepA Enhances Plant Resistance to Citrus Chlorotic Dwarf-Associated Virus by Transcriptionally Activating ClAOS.

JinFa Zhao, ShiYu Zhang, Jie Dong, Yuan Chen, Yan Zhou

Abstract read
In one paragraph

Article in Molecular plant pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

JinFa ZhaoIntegrative Science Center of Germplasm Creation in Western China (Chongqing) Science City/Citrus Research Institute, Southwest University, Chongqing, China.
ShiYu ZhangIntegrative Science Center of Germplasm Creation in Western China (Chongqing) Science City/Citrus Research Institute, Southwest University, Chongqing, China.
Jie DongIntegrative Science Center of Germplasm Creation in Western China (Chongqing) Science City/Citrus Research Institute, Southwest University, Chongqing, China.
Yuan ChenIntegrative Science Center of Germplasm Creation in Western China (Chongqing) Science City/Citrus Research Institute, Southwest University, Chongqing, China.
Yan ZhouIntegrative Science Center of Germplasm Creation in Western China (Chongqing) Science City/Citrus Research Institute, Southwest University, Chongqing, China.

Funding

China Agriculture Research System-Citrus CARS-26-05BWanzhou District Three Gorges Citrus Technology Research Center's Research and Service Project
6 · The paper itself

Abstract

Replication-associated protein A (RepA), encoded by the citrus chlorotic dwarf-associated virus (CCDaV), can activate cell death in the non-host plant Nicotiana benthamiana. However, it remains unknown whether and how it induces immune responses in its citrus host. In this study, we found that RepA overexpression in Eureka lemon enhanced resistance to CCDaV and concomitantly increased jasmonic acid (JA) content. Further study suggested that both JA and its key biosynthetic gene ClAOS positively regulated the antiviral resistance. In addition, yeast one-hybrid and dual-luciferase reporter assay confirmed that RepA functions as a transcription factor, directly binding to the ClAOS promoter to activate its transcription. Collectively, these results delineate how the geminiviral protein transcriptionally reprogrammes host defence metabolism, providing new insights into the modulation of plant immunity by virus-encoded proteins.

Indexed as

CitrusDisease ResistanceGeminiviridaePlant DiseasesPlant ProteinsTranscriptional ActivationViral ProteinsCyclopentanesGene Expression Regulation, PlantNicotianaOxylipinsPromoter Regions, GeneticCyclopentanesjasmonic acidOxylipinsPlant ProteinsViral ProteinsCCDaVClAOSlemon resistanceRepAtranscriptionally activate

Identifiers

PMID41872960
PMCPMC13098075

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.