Evidence map›Paper›PMID 41872939›Full record

ReviewJournal of ovarian research2026

Oxidative stress and the therapeutic potential of dietary antioxidants in polycystic ovary syndrome: a narrative review.

Nevin Adel Amer, Shatha Basheer Aldababseh, Doha Abdel Hady Abdel Gawad, Mostafa M Abdelsadek, Rania Abdel Khalik Gouda, Abdela Befa Kinki

Abstract readReview
In one paragraph

Review in Journal of ovarian research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nevin Adel AmerDepartment of Nursing, College of Applied Medical Sciences- Al- Qurayyat, Jouf University, AL-Qurayyat, Saudi Arabia.
Shatha Basheer AldababsehDepartment of Nursing, College of Applied Medical Sciences- Al- Qurayyat, Jouf University, AL-Qurayyat, Saudi Arabia.
Doha Abdel Hady Abdel GawadDepartment of Medical Surgical Nursing, Faculty of Nursing, Menoufia University, Menoufia, Egypt.
Mostafa M AbdelsadekDepartment of Nursing, College of Applied Medical Sciences- Al- Qurayyat, Jouf University, AL-Qurayyat, Saudi Arabia.
Rania Abdel Khalik GoudaDepartment of Nursing, North Private College of Nursing, Arar, Northen Borders Region, Arar, Saudi Arabia.
Abdela Befa KinkiDepartment of Food Science and Nutrition, Ethiopian Institute of Agricultural Research, Addis Ababa, Ethiopia. befabdela@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is becoming more well acknowledged that oxidative stress is a crucial component that connects the hormonal, metabolic, and reproductive aspects of polycystic ovarian syndrome (PCOS). A more holistic and natural approach to managing the illness might be possible through lowering this disparity. This review outlines new findings about the effects of dietary antioxidants on critical processes related to PCOS, such as insulin signaling, inflammation, and mitochondrial activity. Antioxidants that have demonstrated encouraging effects in reducing oxidative stress, insulin resistance, and ovulatory health include N-acetylcysteine, coenzyme Q10, α-lipoic acid, and vitamins C and E. However, it's challenging to draw definitive findings due to limited intervention periods and variances in the study's methodology. More thorough, deeper, and more extensive standardized trials should be the main emphasis of future studies. Taken together, the results indicate that dietary antioxidants have significant medicinal value to help women with PCOS regain redox equilibrium and enhance their overall metabolic and reproductive health.

Indexed as

AntioxidantsOxidative StressPolycystic Ovary SyndromeAnimalsDietary SupplementsFemaleHumansAntioxidantsCoenzyme Q10N-acetylcysteineOvarian healthRedox imbalanceVitamin C

Identifiers

PMID41872939
PMCPMC13134263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.