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ArticleBMC public health2026

'Ghya Bharaari Ekatra': study protocol for a cluster randomized trial to evaluate a couples-based intervention for the primary prevention of intimate partner violence in India.

Ameeta S Kalokhe, Shahina Begum, Sampada Bangar, Mahadev Bhise, Matthew C Freeman, Tuman Katendra, Girish Rahane, Uday Ravi, Shivani A Patel, Ranjan Prusty and 3 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06811922 (Primary Prevention of Intimate Partner Violence), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06811922 nanot yet recruitingnot on this map

Primary Prevention of Intimate Partner Violence

TypeinterventionalSponsorEmory UniversityRan2026 to 2027Enrolled1,700ConditionsIntimate Partner ViolenceArmsGBE (Ghya Bharaari Ekatra) intervention, Ethical standard of care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ameeta S KalokheDivision of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA. akalokh@emory.edu.
Shahina BegumDepartment of Biostatistics and Socio Behavioral Research, Indian Council of Medical Research National Institute for Research in Reproductive and Child Health, Mumbai, India.
Sampada BangarSocial and Behavioral Research Division, Indian Council of Medical Research National Institute of Translational Virology and AIDS Research, Pune, India.
Mahadev BhiseDepartment of Biostatistics and Socio Behavioral Research, Indian Council of Medical Research National Institute for Research in Reproductive and Child Health, Mumbai, India.
Matthew C FreemanDepartment of Global Health, Emory Rollins School of Public Health, Atlanta, GA, USA.
Tuman KatendraSocial and Behavioral Research Division, Indian Council of Medical Research National Institute of Translational Virology and AIDS Research, Pune, India.
Girish RahaneSocial and Behavioral Research Division, Indian Council of Medical Research National Institute of Translational Virology and AIDS Research, Pune, India.
Uday RaviSocial and Behavioral Research Division, Indian Council of Medical Research National Institute of Translational Virology and AIDS Research, Pune, India.
Shivani A PatelDepartment of Global Health, Emory Rollins School of Public Health, Atlanta, GA, USA.
Ranjan PrustyDepartment of Biostatistics and Socio Behavioral Research, Indian Council of Medical Research National Institute for Research in Reproductive and Child Health, Mumbai, India.
Jessica M SalesDepartment of Behavioral, Social, and Health Education Sciences, Emory Rollins School of Public Health, Atlanta, GA, USA.
Susan WirtzDivision of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Seema SahaySocial and Behavioral Research Division, Indian Council of Medical Research National Institute of Translational Virology and AIDS Research, Pune, India.

Funding

Primary Prevention of Intimate Partner ViolenceR01HD114862 · NICHD · EMORY UNIVERSITY · PI Shahina Begum, Ameeta Shivdas Kalokhe · 2024 to 2026
$1.7M
NICHD NIH HHS R01 HD114862
6 · The paper itself

Abstract

backgroundIntimate partner violence (IPV) is experienced by one-fourth of women in India and associated with poor mental, physical, sexual and reproductive health. Ghya Bharaari Ekatra (GBE) is an evidence-based, theory-driven, culturally tailored, dyadic intervention, developed and piloted for the primary prevention of IPV among newly-married, low-income couples residing in urban slums in Maharashtra, India. GBE is delivered over six weekly sessions by a team of lay peer educators to groups of five couples and makes use of engaging culturally-tailored delivery methods to challenge norms and build knowledge and skills to address key IPV determinants. This manuscript outlines the protocol for the quantitative evaluation of GBE’s total impact on IPV, mental health, and reproductive autonomy, with consideration of mediating and moderating factors.

methodsWe will conduct a cluster randomized trial among 850 newly married dyads (500 assigned to GBE and 350 controls) in two districts in Maharashtra, India to quantify the impact of the GBE intervention compared to the ethical standard of care (information on IPV and mental and reproductive/sexual health resources) in preventing IPV experience (primary outcome) at 12 months. Secondary outcomes include reproductive autonomy among the newly married women and mental health among both members of the dyad at 12 months. We will also conduct mediation and moderation analyses for the efficacy of the GBE intervention. DISCUSSION: Study findings will provide insight into GBE’s potential to prevent IPV, its mechanism of effect, and contexts that may modify its effects, thereby facilitating future scale-up across India and similar resource-limited, high-burden settings globally upon study completion.

trial registrationRegistered at ClinicalTrials.gov on 6th February 2025: NCT06811922. Registered at Clinical Trials Registry-India (CTRI) on 3rd December 2024 : REF/2024/12/095719.

Indexed as

Intimate Partner ViolencePrimary PreventionAdultFemaleHumansIndiaMaleMental HealthPoverty AreasRandomized Controlled Trials as TopicCouplesDomestic violenceIndiaIntimate partner violenceMental healthPreventionReproductive autonomySpousal abuse

Identifiers

PMID41872785
PMCPMC13202749

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.