ArticleBMC pediatrics2026
Laparoscopic polidocanol foam sclerotherapy for retroperitoneal lymphatic malformations in children: a single center retrospective study.
Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundRetroperitoneal lymphatic malformations (LMs) are rare, and their deep location adjacent to critical structures renders treatment particularly challenging. This retrospective study aims to investigate the safety and efficacy of laparoscopic polidocanol foam sclerotherapy (LPFS) in the treatment of retroperitoneal LMs in children.
methodsWe conducted a retrospective analysis of 12 pediatric patients with retroperitoneal LMs who underwent LPFS at our institution between July 2020 and July 2025. The procedure involved laparoscopic-guided cyst puncture, aspiration, and injection of polidocanol foam prepared using the Tessari technique. Key outcomes included operative details, number of treatment sessions, complications, and treatment response defined by imaging.
resultsAll 12 patients were successfully completed laparoscopically without conversion to open surgery. The cohort comprised 2 macrocystic and 10 mixed LMs, with a median maximum diameter of 8.6 cm (range: 5.3–19.3 cm). Intracystic hemorrhage was noted intraoperatively in 9 cases and adhesions in 5 cases. Complete radiologic resolution was ultimately achieved in all patients. 10 patients required only a single treatment session, while the remaining 2 achieved complete resolution after a second LPFS session. All ten patients who presented with preoperative symptoms reported complete and sustained resolution. No major complications, such as vascular injury, visceral organ damage, or clinical evidence of adhesion-related obstruction, were observed. During a median follow-up of 36 months (range: 7–60 months), there were no cases of recurrence.
conclusionLPFS is a safe and effective minimally invasive treatment for pediatric retroperitoneal lymphatic malformations. It may represent a feasible option, particularly for lesions in anatomically complex locations.
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