Evidence map›Paper›PMID 41872724›Full record

ArticleJournal of cataract and refractive surgery2026

Role of toric intraocular lenses in the correction of keratoconic eyes with cataract.

Sharon M Francis, Luc Van Os, Carina Koppen, Jos J Rozema

Abstract read
In one paragraph

Article in Journal of cataract and refractive surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Sharon M FrancisFrom the Visual Optics Lab Antwerp (VOLANTIS), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium (Francis, Rozema); Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium (Van Os, Koppen, Rozema); Institute for Medical Informatics, Statistics, and Epidemiology (IMISE), Leipzig University, Leipzig, Germany (Rozema).ORCID 0000-0003-0454-1966

Funding

University of Antwerp DOCPRO4 - 48121
6 · The paper itself

Abstract

purposeTo investigate the optimal intraocular lens (IOL) corrections for virtual eyes with moderate to severe keratoconus (KC) using ray tracing and comparative analysis of image quality.

settingComputer simulations conducted using MATLAB-based custom ray-tracing software.

designThe study included 20 eyes generated from a statistical eye model called SyntEyes, which produces eye biometrics for KC eyes for optical simulation. The visual Strehl ratio (VSX) was used to quantify image quality based on optical wavefront analysis.

methodsThe eyes underwent various simulated corrections, including spherical and toric IOLs, as well as spherical and toric rigid gas-permeable (RGP) contact lenses, both individually and in combination. Comparisons were made across different correction strategies.

resultsSpherical and toric IOLs alone modestly improved VSX to 0.025 ± 0.004 and 0.034 ± 0.005, respectively, from a baseline of 0.013 ± 0.003 (P < .001). By contrast, eyes corrected with toric RGP lenses after IOL implantation demonstrated significantly higher image quality: 0.250 ± 0.014 (spherical IOL) and 0.246 ± 0.014 (toric IOL) (P < .001). However, combining 2 toric elements often led to overcorrection and increased aberrations.

conclusionsIOL corrections alone are insufficient to compensate for large corneal aberrations present in KC eyes. Subsequent fitting with toric RGP lenses can restore most eyes to normal levels of visual image quality. Among the compared IOL corrections, the combination of a spherical IOL with a toric IOL gave the best average VSX on average and avoids chances of overcorrection.

Indexed as

CataractKeratoconusLenses, IntraocularLens Implantation, IntraocularAstigmatismBiometryComputer SimulationCorneal TopographyCorneal Wavefront AberrationHumansPhacoemulsificationProsthesis DesignRefraction, OcularVisual Acuity

Identifiers

PMID41872724
PMCPMC12998756

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.