Evidence map›Paper›PMID 41872694›Full record

ArticlePediatric transplantation2026

Sociodemographic and Clinical Factors Impact Non-Live Vaccine Coverage After Pediatric Solid Organ Transplantation: A Single Center Study.

Adam Z Blatt, Yunfei Wang, Yeh-Chung Chang, Sarah M Heston

Abstract read
In one paragraph

Article in Pediatric transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adam Z BlattLevine Children's Hospital, USA.ORCID 0000-0002-6363-3089
Yunfei WangDuke University Human Vaccine Institute, USA.ORCID 0000-0002-3205-6338
Yeh-Chung ChangDepartment of Pediatrics, The University of Texas Southwestern Medical Center, USA.ORCID 0000-0003-3073-4980
Sarah M HestonDepartment of Pediatrics, Duke University, USA.ORCID 0000-0001-6150-1149

Funding

Duke Center for Advancement of Child Health (CAtCH)K12HD105253 · NICHD · DUKE UNIVERSITY · PI Corinne Mary Linardic, Ann M. Reed · 2021 to 2026
$1.5M
The Gut Microbiome and Development of Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation in ChildrenK23HL177148 · NHLBI · DUKE UNIVERSITY · PI Sarah Mabrey Heston · 2025 to 2026
$323k
Children's Miracle Network HospitalsNational Institute of Child Health and Human Development K12HD105253NHLBI NIH HHS K23 HL177148NHLBI NIH HHS K23HL177148NICHD NIH HHS K12 HD105253NIH HHS
6 · The paper itself

Abstract

backgroundPediatric solid organ transplant (SOT) recipients are at increased risk of vaccine preventable diseases (VPD) due to both under-vaccination and ineffective responses to vaccines while immunosuppressed. Current guidelines recommend timely post-transplant immunization with non-live vaccines and surveillance of vaccine-specific titers to assess vaccine responses; however, institutional adherence to these recommendations may be variable.

methodsThis single-center retrospective study of 199 pediatric SOT recipients (59 heart, 10 intestinal/multi-visceral, 34 kidney, and 96 liver) evaluated guideline adherence to post-vaccine serologic monitoring and identified sociodemographic and clinical factors associated with delayed and incomplete schedules for routine childhood non-live vaccines after transplant.

resultsSerologic monitoring was utilized after only 8% of recommended vaccines, while participants' age at transplant (odds ratio [OR], 95% confidence interval [CI]: 0.86, 0.81-0.91), receipt of a heart transplant (OR, 95% CI: 0.32, 0.17-0.60), and coverage with private insurance (OR, 95% CI: 0.46, 0.25-0.85) were factors negatively associated with timely initiation or completion of non-live vaccines after transplant.

conclusionsThe associations between age at transplant, heart transplantation, and type of insurance with under-immunization warrant further investigation to address modifiable gaps in vaccine coverage and ensure pediatric SOT recipients are optimally protected from VPD.

Indexed as

Organ TransplantationVaccinationVaccination CoverageVaccinesAdolescentChildChild, PreschoolFemaleGuideline AdherenceHumansInfantMaleRetrospective StudiesSocioeconomic FactorsVaccinespediatricsolid organtransplantvaccines

Identifiers

PMID41872694
PMCPMC13009305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.