Evidence map›Paper›PMID 41872649›Full record

ArticleInternational urology and nephrology2026

Biomechanic characterization of normal urethra using uro-dynamic MRI during voiding.

Cody Johnson, Juan Pablo Gonzalez-Pereira, Maxwell Kounga, Wade Bushman, Alejandro Roldan-Alzate

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Cody JohnsonDepartment of Radiology, University of Wisconsin-Madison, Madison, USA.ORCID http://orcid.org/0000-0003-3028-406X
Juan Pablo Gonzalez-PereiraDepartment of Mechanical Engineering, University of Wisconsin-Madison, Madison, USA.ORCID http://orcid.org/0000-0002-3580-3570
Maxwell KoungaDepartment of Radiology, University of Wisconsin-Madison, Madison, USA.ORCID http://orcid.org/0009-0001-3530-1191
Wade BushmanDepartment of Urology, University of Wisconsin-Madison, Madison, USA. bushman@urology.wisc.edu.
Alejandro Roldan-AlzateDepartment of Mechanical Engineering, Department of Radiology, Department of Biomedical Engineering, Department of Urology, University of Wisconsin-Madison, Madison, USA.

Funding

MR imaging-based Quantitative Analysis of Bladder Anatomy and Function in BPH/LUTSR01DK126850 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI ROLDAN, ALEJANDRO · 2021 to 2023
$680k
NIDDK NIH HHS R01 DK126850NIDDK NIH HHS R01 DK126850-01
6 · The paper itself

Abstract

introductionDynamic volumetric MRI was used to non-invasively assess urethral biomechanics in a single healthy male subject during voiding.

methodsVolumetric lower urinary tract (LUT) images were obtained throughout the voiding effort using the uro-dynamic MRI methodology. These were subsequently segmented using MIMICS. Segmented urethral volumes were divided into prostatic, membranous, penile and bulbous urethra and were used to quantify urethral diameters over time, length and different phases of flow. Idealized instantaneous resistances were calculated for the posterior (prostatic and membranous) urethra.

resultsThe analysis was separated into time and length averaged, and step-by-step analysis. Step-by-step analysis revealed more variation in the initial flow and terminal flow than during robust flow. Time and length averaged analysis showed the membranous urethra had the narrowest lumen and greatest resistance to flow. Correlation of urethral diameters with flow showed strong correlations with both the prostatic and membranous urethral segments.

conclusionThis single-subject study confirms the potential of uro-dynamic MRI to provide noninvasive assessment of lower urinary tract anatomy and urethral biomechanics during voiding.

Indexed as

Magnetic Resonance ImagingUrethraUrinationAdultBiomechanical PhenomenaHumansMaleUrodynamicsAnterior urethraDynamic MRIPosterior urethraUrethral biomechanicsUrethral diameterUrethral resistance

Identifiers

PMID41872649
PMCPMC13506545

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.