Evidence map›Paper›PMID 41872645›Full record

ArticlePharmaceutical research2026

Development of a Dual-Isotope Imaging Technique for Simultaneous Quantification and Evaluation of Biodistribution of Antibodies Using "XCam-CdTe".

Miho Nagayasu, Miho Katsuragawa, Kazuhisa Ozeki, Shinichiro Takeda, Kei Higashikawa, Atsushi Yagishita, Atsushi Ochiai, Kimio Terao, Tadayuki Takahashi

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Article in Pharmaceutical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miho NagayasuTranslational Research Division, Chugai Pharmaceutical Co., Ltd., 216 Totsuka-cho, Totsuka-ku, Yokohama, Kanagawa, 244-8602, Japan.
Miho KatsuragawaDivision of Physics and Astronomy, Graduate School of Science, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto, 606-8502, Japan.
Kazuhisa OzekiTranslational Research Division, Chugai Pharmaceutical Co., Ltd., 216 Totsuka-cho, Totsuka-ku, Yokohama, Kanagawa, 244-8602, Japan. ozekikzh@chugai-pharm.co.jp.
Shinichiro TakedaKavli Institute for the Physics and Mathematics of the University (IPMU, WPI), The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8583, Japan.
Kei HigashikawaTranslational Research Division, Chugai Pharmaceutical Co., Ltd., 2-1-1 Nihonbashi-Muromachi, Chuo-ku, Tokyo, 103-8324, Japan.
Atsushi YagishitaKavli Institute for the Physics and Mathematics of the University (IPMU, WPI), The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8583, Japan.
Atsushi OchiaiResearch Institute for Biomedical Sciences, Tokyo University of Science, 2669 Yamazaki, Noda-shi, Chiba, 278-0022, Japan.
Kimio TeraoTranslational Research Division, Chugai Pharmaceutical Co., Ltd., 2-1-1 Nihonbashi-Muromachi, Chuo-ku, Tokyo, 103-8324, Japan.
Tadayuki TakahashiKavli Institute for the Physics and Mathematics of the University (IPMU, WPI), The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8583, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe tissue distribution of

methodsFollowing intravenous administration of

resultsThe plasma concentration-time profiles of both labeled antibodies up to 72 h post-dose were consistent between radionuclides and comparable to typical antibodies. The

conclusionsThese results suggested that the XCam-CdTe measurement captured the typical pharmacokinetic characteristics of

Indexed as

Indium RadioisotopesIodine RadioisotopesTelluriumAnimalsCadmium CompoundsCell Line, TumorFemaleHumansMiceTissue DistributionCadmium Compoundscadmium tellurideIndium-111Indium RadioisotopesIodine-125Iodine RadioisotopesTelluriumbiodistributionCdTe detectordual-isotope imagingradiolabeled antibodiestumor distribution

Identifiers

PMID41872645

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.