Evidence map›Paper›PMID 41872375›Full record

ArticleEJNMMI physics2026

Performance of high-resolution PET detectors consisting of long GAGG slabs with different reflectors.

Zhonghua Kuang, Samuel Mungai Kinyanjui, Ling Zhang, Ning Ren, Zheng Liu, Qiaolai Tan, Jianquan Huang, Zhanli Hu, Yongfeng Yang

Abstract read
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Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

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9 authors.

Zhonghua KuangMicroelectronics and Optoelectronics Technology Key Laboratory of Hunan Higher Education, School of Physics and Electronic Electrical Engineering, Xiangnan University, Chenzhou, 423000, China.ORCID http://orcid.org/0000-0002-6848-1635
Samuel Mungai KinyanjuiPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Ling ZhangMicroelectronics and Optoelectronics Technology Key Laboratory of Hunan Higher Education, School of Physics and Electronic Electrical Engineering, Xiangnan University, Chenzhou, 423000, China.
Ning RenPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Zheng LiuPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Qiaolai TanMicroelectronics and Optoelectronics Technology Key Laboratory of Hunan Higher Education, School of Physics and Electronic Electrical Engineering, Xiangnan University, Chenzhou, 423000, China.
Jianquan HuangMicroelectronics and Optoelectronics Technology Key Laboratory of Hunan Higher Education, School of Physics and Electronic Electrical Engineering, Xiangnan University, Chenzhou, 423000, China.
Zhanli HuPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Yongfeng YangPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. yf.yang@siat.ac.cn.ORCID http://orcid.org/0000-0003-1642-6631

Funding

Basic Research Program of Shenzhen JCYJ20241202124959061Key Laboratory for Magnetic Resonance and Multimodality Imaging of Guangdong Province 2023B1212060052National Natural Science Foundation of China 12375358National Natural Science Foundation of China 62101539Natural Science Foundation of Hunan Province 2024JJ6414Scientific Research Fund of Hunan Provincial Education Department 25B0766Teaching Reform Research Project of Xiangnan University XNJG202436
6 · The paper itself

Abstract

backgroundDepth of interaction (DOI) encoding detectors are essential for pre-clinical or organ-dedicated PET scanners to simultaneously achieve high spatial resolution and high sensitivity. Semi-monolithic scintillator PET detectors inherently possess the DOI encoding capability that monolithic scintillator detectors have and can also improve the spatial resolution of the detector by reducing the edge effect. Compared to the widely used lutetium yttrium oxyorthosilicate (LYSO) scintillator, the newly developed gadolinium aluminum gallium garnet (GAGG) scintillator has a higher light output, which may lead to a better energy resolution and higher three-dimensional positioning accuracy in semi-monolithic PET detectors.

methodsThe semi-monolithic scintillator detectors consisted of 12 long GAGG slabs of 0.96 ⋅ 56 ⋅ 10 mm

resultsAll slabs are clearly identified from the flood histograms of both detectors. The average peak-to-valley ratios (PVRs), calculated from the line profiles through the center y-axis of the flood histograms, are 3.96 and 3.55 for detectors 1 and 2, respectively. The average energy resolutions are 15.6 ± 1.8% for detector 1 and 14.7 ± 1.2% for detector 2. The COG method provides y-position resolutions of 2.21 ± 0.77 mm for detector 1 and 2.16 ± 0.55 mm for detector 2, whereas the squared COG method provides y-position resolutions of 1.60 ± 0.32 mm and 1.59 ± 0.26 mm, respectively. The average DOI resolutions are 2.33 ± 0.68 mm for detector 1 and 2.37 ± 0.58 mm for detector 2. The average timing resolutions are 4.30 ± 0.57 ns for detector 1 and 4.76 ± 0.56 ns for detector 2. Compared to the detector using LYSO scintillator slabs, the detector using GAGG scintillator slabs provides similar y-position and DOI resolutions, a better energy resolution, a better PVR in the flood histogram and a worse timing resolution.

conclusionIn this work, the performance of two semi-monolithic scintillator detectors composed of GAGG slabs was investigated for the first time. The detector using the ESR reflector achieved similar y-position and DOI resolutions, slightly better energy resolution, and a poorer flood histogram compared to the detector using the BaSO

Indexed as

Depth of interaction (DOI)Gadolinium aluminum gallium garnet (GAGG)Positron emission tomography (PET)Semi-monolithic scintillator detectorSilicon photomultiplier (SiPM)

Identifiers

PMID41872375
PMCPMC13046888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.