Evidence map›Paper›PMID 41872225›Full record

ArticleScientific data2026

A preclinical CT and MRI Liver Imaging Dataset with Anatomical, Functional and Segmentation Data.

Sarah Schraven, Catherine Gonzalez, Ferhan Baskaya, Lara Krott, Anika Beckers, Renée Michèle Girbig, Ramona Brück, Diana Möckel, Marie-Luise Berres, Kai Markus Schneider and 2 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sarah SchravenRWTH Aachen University, Institute for Experimental Molecular Imaging, Aachen, Germany.
Catherine GonzalezRWTH Aachen University, IT Center, Aachen, Germany.
Ferhan BaskayaRWTH Aachen University, Institute for Experimental Molecular Imaging, Aachen, Germany.
Lara KrottRWTH Aachen University, Institute for Experimental Molecular Imaging, Aachen, Germany.
Anika BeckersDepartment of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Renée Michèle GirbigRWTH Aachen University, Institute for Experimental Molecular Imaging, Aachen, Germany.
Ramona BrückRWTH Aachen University, Institute for Experimental Molecular Imaging, Aachen, Germany.
Diana MöckelRWTH Aachen University, Institute for Experimental Molecular Imaging, Aachen, Germany.
Marie-Luise BerresDepartment of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Kai Markus SchneiderDepartment of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.ORCID 0000-0002-0047-3794
Angela SchippersDepartment of Pediatrics, University Hospital RWTH Aachen, Aachen, Germany.
Fabian KiesslingRWTH Aachen University, Institute for Experimental Molecular Imaging, Aachen, Germany. fkiessling@ukaachen.de.ORCID 0000-0002-7341-0399

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) INST222/1261-1Deutsche Forschungsgemeinschaft (German Research Foundation) Project-ID 321137804 - FOR2591Deutsche Forschungsgemeinschaft (German Research Foundation) Project-ID 403224013 - SFB 1382
6 · The paper itself

Abstract

Chronic liver diseases (CLD) account for more than 2% of deaths worldwide. Extensive research has been conducted to better understand CLD, generating vast amounts of data. However, only a small fraction of raw preclinical data are publicly available, posing a significant challenge for transparency, reproducibility, and data reuse. Therefore, we built a preclinical liver imaging dataset, the first of its kind to our knowledge. The database contains longitudinal liver MRI scans from mice with hepatocellular carcinoma, metabolic dysfunction-associated steatohepatitis (MASH, formerly NASH), and fibrosis, as well as CT scans of mice with MASH and mice carrying a dysfunctional ICAM-1 gene. Superimposable MRI and CT scans bridge the gap between the modalities. Some of the 222 murine scans have annotated segmentations. Metadata containing both scan and mouse parameters are organized using a tailored metadata profile in ISA-Tabs. This dataset enables advanced image analysis, such as building tools for automated segmentation, train radiomics analysis tools, or can be used as a reference control dataset.

Indexed as

LiverLiver DiseasesMagnetic Resonance ImagingTomography, X-Ray ComputedAnimalsCarcinoma, HepatocellularLiver NeoplasmsMiceRadiomics

Identifiers

PMID41872225
PMCPMC13013689

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.