Evidence map›Paper›PMID 41871869›Full record

ArticleBMJ global health2026

A WHO global research priority agenda for wasting and nutritional oedema in infants and children under 5 years.

Allison I Daniel, Jaden Bendabenda, Michael McCaul, Celeste E Naude, Marina Adrianopoli, Zita Weise Prinzo

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Article in BMJ global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Allison I DanielConsultant to the World Health Organization, Geneva, Switzerland adaniel@who.int.ORCID 0000-0002-1774-1214
Jaden BendabendaDepartment of Nutrition and Food Safety, World Health Organization, Geneva, Switzerland.
Michael McCaulCentre for Evidence-based Health Care, Division of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University, Cape Town, South Africa.
Celeste E NaudeCentre for Evidence-based Health Care, Division of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University, Cape Town, South Africa.ORCID 0000-0002-9114-1452
Marina AdrianopoliDepartment of Nutrition and Food Safety, World Health Organization, Geneva, Switzerland.
Zita Weise PrinzoDepartment of Nutrition and Food Safety, World Health Organization, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe guideline development process for the WHO guideline on prevention and management of wasting and nutritional oedema highlighted extensive evidence gaps. We, the WHO Steering Committee and methodologists for the 2023 WHO guideline, therefore aimed to develop a comprehensive global research priority agenda for wasting and nutritional oedema in infants and children. It has a timeframe up to 2030 aligning with the Sustainable Development Goals and Global Nutrition Targets related to wasting and nutritional oedema.

methodsWe used a Child Health and Nutrition Research Initiative (CHNRI) exercise to develop this research priority agenda for four populations and topics of interest: (1) infants less than 6 months of age at risk of poor growth and development; (2) infants and children 6-59 months of age with severe wasting and/or nutritional oedema; (3) infants and children 6-59 months of age with moderate wasting and (4) prevention of wasting and nutritional oedema. For this CHNRI process, we conducted two anonymous surveys, the first to ensure the list of research questions was comprehensive and clear, and the second to score research questions based on their answerability, effectiveness, deliverability and effects on equity.

results63 people from 28 countries completed survey 1 and 50 people from 23 countries completed survey 2. We identified 10 priority research questions for each of the four populations and topics of interest, which had median research priority scores of 89.9 (IQR 2.8) and average expert agreement scores with a median of 83.4 (IQR 4.5) indicating high agreement. The research questions are largely focused on delivery and effectiveness of interventions for prevention and management of wasting and nutritional oedema rather than discovery or development.

conclusionsThis research priority agenda will guide researchers and research institutions, funders and others to address pressing research questions on wasting and nutritional oedema.

Indexed as

EdemaResearchWasting SyndromeChild, PreschoolEvidence GapsGlobal HealthHumansInfantWorld Health OrganizationChild healthDecision MakingGlobal HealthNutritionStudy design

Identifiers

PMID41871869
PMCPMC13034320

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.