ArticleBehavioural brain research2026
Progressive gait and motor deficits in a rat model of Alexander disease.
Robert F Berman, Matthew R Matson, Angelica M Bachman, Albee Messing, Tracy L Hagemann
Abstract read
In one paragraphArticle in Behavioural brain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
5 authors.
Robert F BermanUC Davis M.I.N.D. Institute, University of California Davis, Davis, CA 95816, USA; Department of Neurological Surgery, Univ. California Davis, Sacramento, CA 95816, USA.
Matthew R MatsonUC Davis M.I.N.D. Institute, University of California Davis, Davis, CA 95816, USA.
Angelica M BachmanUC Davis M.I.N.D. Institute, University of California Davis, Davis, CA 95816, USA.
Albee MessingDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA.
Tracy L HagemannWaisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA. Electronic address: tlhagemann@wisc.edu.
Funding
UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6MResearch Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7MWaisman Center Intellectual and Developmental Disabilities Research CenterP50HD105353 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Qiang Chang · 2021 to 2026
$8.5MWaisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MESSING, ALBEE · 2016 to 2020
$6.0MPatient-derived iPS cells as model systems for AxDP01HD076892 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI NEDERGAARD, MAIKEN · 2014 to 2018
$6.0MAstrocyte-synapse interactions in a rat model of Alexander diseaseR01NS110719 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI HAGEMANN, TRACY · 2019 to 2023
$2.1MNCI NIH HHS P30 CA014520NICHD NIH HHS P01 HD076892NICHD NIH HHS P50 HD103526NICHD NIH HHS P50 HD105353NICHD NIH HHS U54 HD090256NINDS NIH HHS R01 NS110719
6 · The paper itselfAbstract
Alexander disease is a leukodystrophy caused by gain-of-function mutations in the gene for Glial Fibrillary Acidic Protein (GFAP) which result in accumulation and aggregation of GFAP protein, astrocyte dysfunction, and ultimately developmental delay, failure to thrive, and intellectual and motor impairment. A Gfap
Indexed as
Alexander DiseaseGaitAnimalsCerebellumDisease Models, AnimalDisease ProgressionGlial Fibrillary Acidic ProteinHumansMaleMotor ActivityRatsRats, TransgenicRotarod Performance TestGfap protein, ratGlial Fibrillary Acidic ProteinAlexander diseaseGait analysisGFAP mutationLeukodystrophyOpen fieldRosenthal fibersRotarod
Identifiers
PMID41871689
PMCPMC13095237
What OpenQuestion holds
Textmetadata
LicenceTDM
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