Evidence map›Paper›PMID 41871623›Full record

Trial reportArquivos de neuro-psiquiatria2026

The Acute Effect of Methylphenidate Ingestion in a Visuomotor Task at Absolute Power Alpha in Healthy Subjects.

Vinicius Lourenço, Carlos Amoroso, Renan Vicente, André Azevedo, Eduardo Nicoliche, Bruna Velasques, Marcelo Nobre, Mauricio Cagy, Pedro Ribeiro, Henning Budde and 11 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Arquivos de neuro-psiquiatria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Vinicius LourençoUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-4204-6977
Carlos AmorosoUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0009-0001-0849-1225
Renan VicenteUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0000-0003-4087-2711
André AzevedoEscola Superior de Guerra, Rio de Janeiro RJ, Brazil.ORCID 0009-0003-7433-0002
Eduardo NicolicheUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-2607-5604
Bruna VelasquesUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0000-0001-9363-8932
Marcelo NobreUniversidade Federal do Rio de Janeiro, Escola de Educação Física e Desportos, Rio de Janeiro RJ, Brazil.ORCID 0000-0003-3058-3780
Mauricio CagyUniversidade Federal do Rio de Janeiro, Coordenação dos Programas de Pós-Graduação e Pesquisa de Engenharia, Programa de Engenharia Biomédica, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-6488-842X
Pedro RibeiroUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0000-0001-8270-3663
Henning BuddeMedical School Hamburg, Faculty of Human Sciences, Hamburg, Germany.ORCID 0000-0003-3526-0569
Alex VasconcelosUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0000-0001-6169-3937
Renato FonsecaUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0009-0002-9234-7732
Giovanna ZanchettaUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0009-0006-1722-722X
Marco OrsiniUniversidade Federal Fluminense, Hospital Universitário Antônio Pedro, Niterói RJ, Brazil.ORCID 0000-0002-8526-6937
Marcos MachadoUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-8742-365X
Sávio BarretoUniversidade Federal do Rio de Janeiro, Coordenação dos Programas de Pós-Graduação e Pesquisa de Engenharia, Programa de Engenharia Biomédica, Rio de Janeiro RJ, Brazil.ORCID 0009-0002-0013-3172
Silmar TeixeiraMedical School Hamburg, Faculty of Human Sciences, Hamburg, Germany.ORCID 0000-0002-9240-1228
Victor Hugo BastosMedical School Hamburg, Faculty of Human Sciences, Hamburg, Germany.ORCID 0000-0001-7425-4730
Francisco Victor MarinhoMedical School Hamburg, Faculty of Human Sciences, Hamburg, Germany.ORCID 0000-0003-4800-7298
Isabelle FernandesUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-3088-8325
Egídio NardiUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-2152-4669

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylphenidate (MPH) is a psychostimulant widely used to enhance attention and executive functions through increased dopaminergic and noradrenergic transmission. Although its effects on cognitive performance are well documented, its acute influence on cortical oscillatory activity, particularly α power, during tasks requiring simultaneous motor and cognitive processing remains poorly understood in healthy adults.To investigate the acute effects of 10 mg MPH on absolute α power (8-12 Hz) in frontal regions during a visuomotor task in healthy subjects.A total of 13 right-handed healthy adults (7 men; age 25.6 ± 4.5 years) participated in a randomized, double-blind, placebo-controlled, crossover study. A 20-channel electroencephalography (EEG) was recorded before and after execution of the MIRA visuomotor task (joystick response when a moving target crosses a previously memorized position) under placebo and MPH (10 mg) conditions, with sessions 1 week apart. Absolute α power was compared using two-way ANOVA (condition vs. moment: pre- vs. post-joystick press), followed by paired

Indexed as

Alpha RhythmCentral Nervous System StimulantsMethylphenidatePsychomotor PerformanceAdultAnalysis of VarianceCognitionCognitive EnhancementCross-Over StudiesDouble-Blind MethodElectroencephalographyFemaleHumansMaleTime FactorsYoung AdultCentral Nervous System StimulantsMethylphenidate

Identifiers

PMID41871623
PMCPMC13008493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.