Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Diyendo MassilaniDepartment of Genetics, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0003-2661-4468
Stéphane PeyrégneDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.ORCID 0000-0002-9823-9102
Leonardo N M IasiDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
Cesare de FilippoDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.ORCID 0000-0002-2218-4942
Fabrizio MafessoniDepartment of Life Sciences, University of Trieste, Trieste 34127, Italy.ORCID 0000-0003-4319-2076
Alba Bossoms MesaDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
Arev P SümerDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
Yaniv SwielDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
Divyaratan PopliDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
Shahar SilvermanDepartment of Genetics, Yale School of Medicine, New Haven, CT 06510.
Michael James BoyleDepartment of Genetics, Yale School of Medicine, New Haven, CT 06510.
Maxim B KozlikinInstitute of Archaeology and Ethnography of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0000-0001-5082-3345
Michael V ShunkovInstitute of Archaeology and Ethnography of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0000-0003-1388-2308
Anatoly P DereviankoInstitute of Archaeology and Ethnography of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0000-0003-1156-8331
Tom HighamDepartment of Evolutionary Anthropology, Faculty of Life Sciences, University of Vienna, Vienna 1030, Austria.ORCID 0000-0002-5949-598X
Katerina DoukaDepartment of Evolutionary Anthropology, Faculty of Life Sciences, University of Vienna, Vienna 1030, Austria.ORCID 0000-0002-0558-0011
Matthias MeyerDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
Hugo ZebergDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
Janet KelsoDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.ORCID 0000-0002-3618-322X
Svante PääboDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.ORCID 0000-0002-4670-6311
Funding
Tracing the evolutionary history of human adaptive traits through ancient DNADP2GM159182 · NIGMS · YALE UNIVERSITY · PI MASSILANI, DIYENDO · 2024 to 2024
$1.5M
EC | European Research Council (ERC) 694707HHS | National Institutes of Health (NIH) DP2- 1DP2GM159182-01NIGMS NIH HHS DP2 GM159182Russian Science Foundation (RSF) 24-18-00069
6 · The paper itself
Abstract
We present a genome sequenced to ~37-fold genomic coverage from an approximately 110,000-y-old male Neandertal from Denisova Cave in the Altai Mountains and analyze it together with previously published Neandertal genomes of high quality. We show that he belonged to a population more closely related to a ~120,000-y-old Neandertal from Denisova Cave than to Neandertals in Europe or to a ~80,000-y-old Neandertal from Chagyrskaya Cave in the Altai Mountains. Both Neandertals from Denisova Cave show evidence of gene flow from Denisovans, a pattern not seen in later Neandertals from the Altai region or from Western Europe. The extent of chromosomal regions of homozygosity in Neandertals from the Altai region between 120,000 and 80,000 y ago indicates that they lived in smaller and more isolated groups than later Neandertals in Europe (54,000 to 40,000 y ago). We estimate the extent of allele frequency differentiation among Neandertal populations and find that the older Eastern Neandertals in the Altai region and younger Western Neandertals in Europe were as differentiated as the most differentiated present-day human populations worldwide.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals. · full record | OpenQuestion