Evidence map›Paper›PMID 41871215›Full record

ArticleNeonatology2026

Transfusion Histories of Neonates Who Developed Severe Retinopathy of Prematurity.

Bailey B Zeiler, M Elizabeth Hartnett, Joel L Addams, Elizabeth F Stone, Sarah J Ilstrup, Timothy M Bahr, Robin K Ohls, Robert D Christensen

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Article in Neonatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bailey B ZeilerDivision of Neonatology, Department of Pediatrics, University of Utah, Salt Lake City, Utah, USA, bailey.zeiler@hsc.utah.edu.
M Elizabeth HartnettDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, California, USA.
Joel L AddamsDepartment of Pathology, University of Utah Health, and ARUP Laboratories, Salt Lake City, Utah, USA.
Elizabeth F StoneTransfusion Medicine, Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.
Sarah J IlstrupIntermountain Health Central Laboratories and Transfusion Medicine, Murray, Utah, USA.
Timothy M BahrDivision of Neonatology, Department of Pediatrics, University of Utah, Salt Lake City, Utah, USA.
Robin K OhlsDivision of Neonatology, Department of Pediatrics, University of Utah, Salt Lake City, Utah, USA.
Robert D ChristensenDivision of Neonatology, Department of Pediatrics, University of Utah, Salt Lake City, Utah, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe recent BORN study suggests the incidence of retinopathy of prematurity (ROP) might be significantly reduced by transfusing extremely low gestational age neonates (ELGANs) with red blood cells (RBCs) not from adult donors, but from umbilical cord blood. We are uncertain what proportion of infants with severe ROP had no RBC transfusions and thus would not benefit from changing transfusion practice.

methodsWe created detailed transfusion histories of all infants in our health system (2021-2024) who developed severe ROP.

resultsSevere (stage ≥3) ROP was diagnosed in 34 infants; 32 of these had received 1-18 RBC transfusions. Eleven also received 1-16 platelet transfusions. Two received no transfusions.

conclusionA small minority of infants with severe ROP were never transfused, thus changing transfusion practice would not likely prevent all cases. However, the great majority had multiple RBC transfusions and thus might benefit from cord blood RBC transfusions.

Indexed as

Adult hemoglobinBORNBronchopulmonary dysplasiaExtremely low gestational age neonatesFetal hemoglobinPacked red blood cellsRetinopathy of prematurity

Identifiers

PMID41871215
PMCPMC13197146

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