ArticlePloS one2026
Reliability of durometry to assess firmness of calcinosis lesions in Juvenile and adult dermatomyositis.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectiveDermatomyositis (DM) and juvenile dermatomyositis (JDM) are inflammatory myopathies affecting multiple organs, including muscle and skin. Calcinosis is a complication of DM/JDM that causes significant morbidity; however, few tools exist to assess calcinosis in DM/JDM patients This study aimed to evaluate the reliability of durometry measurements to assess the firmness of calcinosis lesions in DM and JDM patients.
methodsCalcinosis firmness was measured using a handheld digital durometer. Six investigators across 3 institutions examined DM/JDM calcinosis lesions by durometry, as well as control readings in healthy unaffected skin/subcutaneous tissue in similar anatomic areas, recording three readings per site. Intra-rater and inter-rater intraclass correlations were evaluated.
resultsWe enrolled 57 patients and gathered 709 measurements (443 calcinosis lesions; 266 control lesions) over eleven anatomic regions. Intra-rater reliability was high across sites, while inter-rater reliability varied, being moderate to good in most areas, but poor in the thigh and anterior calf. Durometry readings were higher in calcinosis lesions than control sites overall. Measurements moderately correlated with qualitative physician assessments. Due to our study's cross-sectional nature, we could not assess calcinosis over time.
conclusionDurometry is a novel, reliable, quantitative measure in assessing and characterizing targeted calcinosis lesions of DM/JDM patients.
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