Evidence map›Paper›PMID 41870678›Full record

ArticleArchives of gynecology and obstetrics2026

OPM-based fetal magnetocardiography: fetal cardiac time intervals in healthy pregnancies compared to postnatal ECGs.

Annette Wacker-Gussmann, Karin Narushima, Gabriela Tardelli, Ronald T Wakai, Janette F Strasburger, Lena Wunderl, Tobias Jensch, Reinhard Heckel, Silvia M Lobmaier, Nicole Nagdyman and 2 more

Abstract readComparative Study
In one paragraph

Article in Archives of gynecology and obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Annette Wacker-GussmannClinic of Congenital Heart Disease and Pediatric Cardiology, German Heart Center, TUM University Hospital, Technical University of Munich, Munich, Germany. annette.wacker-gussmann@tum.de.
Karin NarushimaClinic of Congenital Heart Disease and Pediatric Cardiology, German Heart Center, TUM University Hospital, Technical University of Munich, Munich, Germany.
Gabriela TardelliDepartment of Medical Physics, University of Wisconsin Madison, Madison, WI, USA.
Ronald T WakaiDepartment of Medical Physics, University of Wisconsin Madison, Madison, WI, USA.
Janette F StrasburgerDepartments of Pediatrics (Cardiology) and Biomedical Engineering Medical College of Wisconsin, Milwaukee, WI, USA.
Lena WunderlChair E66, TUM School of Natural Sciences, Technical University of Munich, Munich, Germany.
Tobias JenschChair E66, TUM School of Natural Sciences, Technical University of Munich, Munich, Germany.
Reinhard HeckelDepartment of Computer Engineering, Information and Technology, TUM School of Computation, Technical University of Munich, Munich, Germany.
Silvia M LobmaierDepartment of Obstetrics and Gynecology, School of Medicine & Health, TUM University Hospital, Technical University of Munich, Munich, Germany.
Nicole NagdymanClinic of Congenital Heart Disease and Pediatric Cardiology, German Heart Center, TUM University Hospital, Technical University of Munich, Munich, Germany.
Peter EwertClinic of Congenital Heart Disease and Pediatric Cardiology, German Heart Center, TUM University Hospital, Technical University of Munich, Munich, Germany.
Peter FierlingerChair E66, TUM School of Natural Sciences, Technical University of Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFetal magnetocardiography (fMCG) is the most accurate method to assess fetal heart rhythm and conduction. New quantum sensor technology makes it possible to use less expensive devices. The aim of the study is to measure cardiac time intervals of healthy fetuses with a new technology, optically pumped magnetometry (OPM), and compare these results with conventional SQUID-based fMCG and postnatal ECGs.

methodsThe recordings were made using an OPM-based fMCG system and a person-sized magnetic shield, established at German Heart Center,TUM University, Munich, Germany. The subjects were 57 healthy women with uncomplicated singleton pregnancies, studied at a mean gestational age of 32 ± 3.7 weeks with an overall range of 25-40 weeks. The P, PR, QRS, QT, QTc, and RR intervals were measured and compared with published data from previous fMCG devices and postnatal ECG.

resultsThe P, PR, and QRS intervals increased with gestational age, but the QT and QTc intervals did not. The measured values of the OPM device were consistent with those from previously published data SQUID values. U-waves were seen in 17.3% of subjects. Eleven subjects were studied by fMCG after 30 weeks' gestation and by ECG within 17 weeks of birth. In this cohort, the P-wave duration, QRS duration, and QTc increased after birth, but the PR and QT intervals did not.

conclusionThe results obtained with our innovative OPM-based fMCG system are comparable to previously available measurements obtained by other technologies. The data establish prediction intervals for OPM-based fMCG waveforms in normal fetuses, which is essential for future clinical application. The technology can be used to recognize fetuses with rhythm or conduction abnormalities that might not be evident by echocardiography. To our knowledge, this is the first report comparing fetal cardiac time intervals measured by OPM-based fMCG with postnatal ECG. Lengthening of cardiac intervals consistent with increased chamber size was seen postnatally.

Indexed as

ElectrocardiographyFetal HeartHeart Rate, FetalMagnetocardiographyMagnetometryAdultFemaleGestational AgeHumansPregnancyFetal cardiologyFetal magnetocardiographyNew technologyNorm valuesOPMSQUID

Identifiers

PMID41870678
PMCPMC13009097

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.