Evidence map›Paper›PMID 41870655›Full record

ArticleLasers in medical science2026

Clinical application of the REVEAL™ fluorescence loupe in oral lesion assessment: a five-case clinical note.

Matheus Albino Souza, Letícia Copatti Dogenski, Gabriele Chitolina, Eduarda Lunelli Ferrari, Gisele Rovani, Liviu Steier, José Antônio Poli de Figueiredo, João Paulo De Carli

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PubMed Full text at PMC Publisher
In one paragraph

Article in Lasers in medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matheus Albino SouzaUniversidade de Passo Fundo, Passo Fundo, Brazil.
Letícia Copatti DogenskiUniversidade de Passo Fundo, Passo Fundo, Brazil. leticiacdogenski@gmail.com.
Gabriele ChitolinaUniversidade de Passo Fundo, Passo Fundo, Brazil.
Eduarda Lunelli FerrariUniversidade de Passo Fundo, Passo Fundo, Brazil.
Gisele RovaniUniversidade de Passo Fundo, Passo Fundo, Brazil.
Liviu SteierUniversity of Pennsylvania, Philadelphia, USA.
José Antônio Poli de FigueiredoFederal University of Rio Grande do Sul, Porto Alegre, Brazil.
João Paulo De CarliUniversidade de Passo Fundo, Passo Fundo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo illustrate the clinical use and feasibility of the REVEAL™ fluorescence loupe as an adjunctive tool in the chairside assessment of inflammatory, potentially malignant, and malignant oral lesions.

methodsFive patients with oral lesions were clinically examined under natural light and with the REVEAL™ loupe. When indicated, biopsy and histopathological analysis were performed

resultsInflammatory lesions exhibited a bright and homogeneous red autofluorescence pattern. Actinic cheilitis demonstrated heterogeneous brownish autofluorescence with whitish areas. Squamous cell carcinomas did not show significant autofluorescence contrast. The presence of biofilm was highlighted by a distinct orange signal.

conclusionThe REVEAL™ loupe may support the clinical assessment of oral lesions by illustrating autofluorescence patterns associated with underlying tissue changes. However, its use should be considered complementary to biopsy, not a diagnostic substitute.

Indexed as

CheilitisMouth DiseasesMouth NeoplasmsOptical ImagingBiopsyCarcinoma, Squamous CellFluorescenceHumansAutofluorescenceDiagnosisOptical imagingOral lesions

Identifiers

PMID41870655
PMCPMC13009011

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