ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026
Von Willebrand disease as a predictor of postoperative hemorrhagic complications in pediatric adenotonsillar surgery: a retrospective cohort study.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHemorrhagic complications after pediatric otolaryngologic surgery are well documented, yet children with bleeding disorders are frequently excluded from clinical studies. Given the prevalence and frequent incidental diagnosis of von Willebrand disease (vWD), accurate assessment of perioperative bleeding risk is essential. This study evaluated the impact of vWD on postoperative hemorrhagic complications following adenotomy (AT) and adenotonsillotomy (ATT) in children.
methodsThis retrospective cohort study included pediatric patients with confirmed vWD who underwent AT or ATT for isolated adenoid hypertrophy or adenoid hypertrophy with tonsillar hypertrophy and the control group. Demographic, clinical, laboratory, and surgical outcome data were collected. Severe postoperative hemorrhage was defined as bleeding requiring posterior nasal packing. Logistic regression analysis was performed to identify predictors of postoperative bleeding.
resultsA total of 134 children were included, comprising 42 patients in the vWD group and 92 patients in the control group. Early postoperative bleeding occurred in 11.9% of patients in the vWD group, with severe bleeding observed in 4.8%. In comparison, the incidence of severe postoperative bleeding in the general surgical population without vWD was 0.83%. The presence of vWD was associated with a nearly sixfold increased risk of severe postoperative hemorrhage (odds ratio 5.99; 95% confidence interval 1.41–25.45; p = 0.049). No significant association was identified between baseline von Willebrand factor antigen or ristocetin cofactor activity levels and postoperative bleeding events.
conclusionsChildren with vWD undergoing AT or ATT have an approximately sixfold higher risk of severe postoperative hemorrhage compared with children without bleeding disorders.
Indexed as
Identifiers
41870578What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.