Evidence map›Paper›PMID 41870152›Full record

GuidelineAge and ageing2026

Best practice guidelines for the diagnosis, evaluation, and management of cognitive disorders in Parkinson's disease.

Dana Pourzinal, Deborah Brooks, Deepa Sriram, Emily Mccann, James M King, Nancy A Pachana, Kirstine Shrubsole, Brian Wood, Alexander Lehn, Rodney Marsh and 9 more

Abstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Age and ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Dana PourzinalThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.ORCID 0000-0001-6712-0080
Deborah BrooksThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Deepa SriramThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Emily MccannThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
James M KingThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Nancy A PachanaThe University of Queensland, School of Psychology, Brisbane, Queensland, Australia.ORCID 0000-0002-8927-4205
Kirstine ShrubsoleThe University of Queensland, Queensland Aphasia Research Centre, Brisbane, Queensland, Australia.
Brian WoodRedland Hospital, Metro South Movement Disorders Service, Cleveland, Queensland, Australia.
Alexander LehnPrincess Alexandra Hospital, Department of Neurology, Woolloongabba, Queensland, Australia.
Rodney MarshThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Jacki LiddleThe University of Queensland, School of Health and Rehabilitation Sciences, Brisbane, Queensland, Australia.
Leander K MitchellThe University of Queensland, School of Psychology, Brisbane, Queensland, Australia.
John D O'SullivanThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Edwin C K TanThe University of Sydney Faculty of Medicine and Health, School of Pharmacy, Sydney, New South Wales, Australia.
Neil PageThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Elton H LoboThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Martie-Louise VerreynneThe University of Queensland, Business School, Brisbane, Queensland, Australia.
Sabrina LenzenThe University of Queensland, Centre for the Business and Economics of Health, Brisbane, Queensland, Australia.
Nadeeka DissanayakaThe University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although cognitive impairment is prevalent in people living with Parkinson's disease (PD), the clinical approach to cognitive disorders in PD varies significantly across health services. Here, we present updated best practice guidelines to standardise the diagnosis, evaluation, and management of cognitive disorders in PD across clinical contexts. Guideline development followed a two-phase process incorporating both expert and lived-experience perspectives. In Phase 1, preparatory research (literature reviews and a national survey) generated 58 preliminary recommendations. These were refined through a modified Delphi process with 29 clinician and research experts, resulting in 51 evidence-based and expert-endorsed recommendations. In Phase 2, perspectives of people with lived experience of cognitive disorders in PD (n = 15) were attained through focus groups, which produced 25 recommendations. A subsequent national survey (n = 81) demonstrated consensus on 24 of the 25 recommendations. Overall, the guideline development process yielded 58 unique recommendations, including recommendations for a tailored neuropsychological toolkit sensitive to cognitive decline in PD. These are the first best practice guidelines for the diagnosis, evaluation and management of cognitive disorders in PD informed by empirical evidence, expert consensus, and insights from people with lived experience. Clinical adoption of these guidelines will improve the quality of care, diagnostic accuracy, and early detection of cognitive disorders in PD. Future service models should consider incorporating these guidelines to optimise cognitive care in PD and promote evidence-based and patient-centred standards of practice.

Indexed as

CognitionCognition DisordersCognitive DysfunctionParkinson DiseaseConsensusDelphi TechniqueEvidence-Based MedicineFocus GroupsHumansNeuropsychological TestsPractice Guidelines as TopicPredictive Value of Testscognitive impairmentdementiaguidelinesolder peopleParkinson’s disease

Identifiers

PMID41870152
PMCPMC13016819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.