ArticlemBio2026
Peptidoglycan DD-peptidases have distinct activities that impact fitness of
Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Organic acid-associated antimicrobial and antibiofilm activity of Lactobacillus rhamnosus ATCC 7469 against Acinetobacter baumannii and Staphylococcus aureus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Outer membrane remodeling via lipid-peptidoglycan crosstalk enables lipooligosaccharide-deficient colistin resistance.Cell reports · 2026Article
Corrections and comments
- Update of
Authors and funding
8 authors.
Funding
Abstract
The gram-negative cell envelope is a critical interface between the bacterium and its environment, serving as a selective barrier for nutrient uptake and defense against harmful agents. It also facilitates environmental sensing and adaptive responses. Structurally, it comprises the outer membrane, inner membrane, and periplasmic space, which contains the peptidoglycan layer-a conserved polymer that maintains cell shape and withstands internal turgor pressure. Peptidoglycan consists of glycan strands connected by short peptides, forming a mesh-like structure. In gram-negative bacteria, most peptidoglycan subunits contain tetrapeptides, generated by DD-carboxypeptidases (DD-CPases) that cleave the terminal D-alanine from pentapeptides. Although gram-negative bacteria encode multiple DD-CPases, their precise roles in maintaining cell shape and structural integrity remain poorly understood. The nosocomial pathogen
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.