Evidence map›Paper›PMID 41869856›Full record

ArticleAmerican journal of physiology. Renal physiology2026

Ovarian hormones moderate systolic hypertension in female

Alethia J Dixon, Ipsita Mohanty, Gagandeep Kaur, James A McCormick, Patrick Osei-Owusu

Abstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Alethia J DixonDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States.
Ipsita MohantyDepartment of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States.ORCID 0000-0003-0894-4770
Gagandeep KaurDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States.
James A McCormickDepartment of Medicine, Oregon Health and Science University, Portland, Oregon, United States.ORCID 0000-0003-4000-6653
Patrick Osei-OwusuDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States.ORCID 0000-0002-4581-7044

Funding

Vascular Pyruvate Kinase M2 in HypertensionR01HL174004 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI SATORU EGUCHI, Patrick Osei-Owusu · 2025 to 2026
$1.4M
Posttranslational regulation of Regulator of G protein Signaling 2 (RGS2)R01GM143493 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SJOGREN, BENITA JENNY · 2022 to 2025
$1.4M
Magnesium handling by the distal nephronR01DK132066 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI JAMES A MCCORMICK · 2023 to 2026
$1.3M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL174004-01HHS | NIH | NIGMS | Native American Research Centers for Health (NARCH) R01GM143493NHLBI NIH HHS R01 HL174004NIDDK NIH HHS R01 DK132066NIGMS NIH HHS R01 GM143493
6 · The paper itself

Abstract

Hypertension is a hallmark of cardiovascular abnormalities associated with Williams syndrome (WS), a rare genetic disorder involving microdeletion of genes on human chromosome 7, including the elastin gene (

Indexed as

Blood PressureElastinHaploinsufficiencyHypertensionKidneyAnimalsDisease Models, AnimalFemaleMiceMice, Inbred C57BLMice, KnockoutNatriuresisOvariectomySodiumElastinSodiumelastin haploinsufficiencyhypertensionovarian hormonesrenal functionvasopressin signaling

Identifiers

PMID41869856
PMCPMC13135837

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.