ArticlePlant, cell & environment2026
Circular RNAs in Lotus japonicus Responses to Nutrient Supply and Mesorhizobium Symbiosis.
Article in Plant, cell & environment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Symbiotic interactions between legumes and rhizobia enable nitrogen fixation under low nutrient conditions. The establishment and function of symbiotic interactions require coordinated changes in gene expression in both the host and the microbe. Circular RNAs (circRNAs) are endogenous gene-specific molecules that can regulate transcription and translation in response to biotic and abiotic stress through various mechanisms. Our objective was to identify circRNAs specifically generated in response to nutrient supply and rhizobial symbiosis. We sequenced nodulated and non-inoculated roots from Lotus japonicus and identified a total of 11,923 putative circRNAs originating from 5,290 nuclear-encoded transcripts in Lotus roots under low or high nutrient supply and nodulated roots. Of those, 58 circRNAs were specific and present in most nodulated root samples. We identified circRNAs for more than half of the known symbiosis-associated genes, including SymRK, CCamK, and Cyclops, and showed that several of those genes also generated circRNAs in Phaseolus vulgaris nodules. We validated select circRNAs potentially involved in regulating symbiosis and predicted miRNA recognition elements (MREs) created only by the backsplice junctions of circRNAs. These putative backsplice-generated MREs could represent an additional mechanism by which circRNAs may modulate the abundance and translation of mRNAs in competing endogenous RNA-regulatory networks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.